Recognizing the pleura in asbestos-related pleuropulmonary disease: Known and new manifestations of pleural fibrosis.

Autor: Miller A; Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Queens, New York, USA.
Jazyk: angličtina
Zdroj: American journal of industrial medicine [Am J Ind Med] 2024 Jan; Vol. 67 (1), pp. 73-80. Date of Electronic Publication: 2023 Nov 29.
DOI: 10.1002/ajim.23553
Abstrakt: Pleural thickening (PT) is a major consequence of exposure to all fiber types of asbestos. In recent decades, it is more prevalent than parenchymal asbestosis. Its manifestations occupy a full clinical and radiographic spectrum. Six major manifestations can be identified: (a) acute pleuritis generally with effusion; (b) diffuse PT or fibrous pleuritis; (c) rounded atelectasis; (d) circumscribed PT or plaques; (e) chronic pleuritic pain; and (f) mesothelioma. Review of the experience of workers and community members in Libby, MT to asbestiform fibers in vermiculite has confirmed the appearance of these previously known benign and malignant asbestos-related diseases as well as a unique pleuropulmonary disease characterized as lamellar PT and associated with progressive decline in pulmonary function and pleuritic pain. Despite previous literature asserting that PT represents a marker for asbestos exposure without significant effect on pulmonary function and physiology, the experience of Libby amphibole (LA) disease, along with other studies, indicates that PT plays a role in declining vital capacity in those with prolonged or unusual exposures such as those arising from LA.
(© 2023 Wiley Periodicals LLC.)
Databáze: MEDLINE
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