Reliability of radioguided occult lesion localization in reoperation of loco-regional persistent/recurrent differentiated thyroid cancer: Retrospective cohort study.

Autor: Cadena-Piñeros E; Department of Head and Neck Surgery, Instituto Nacional de Cancerología, Bogotá, DC, Colombia.; Department of Otorhinolaryngology, Universidad Nacional de Colombia and Hospital Universitario Nacional de Colombia, Bogotá, DC, Colombia., Correa-Marin J; Department of Head and Neck Surgery, Instituto Nacional de Cancerología, Bogotá, DC, Colombia., Llamas-Olier A; Nuclear Medicine Department, Instituto Nacional de Cancerología, Bogotá, DC, Colombia., de Los Reyes A; Nuclear Medicine Department, Instituto Nacional de Cancerología, Bogotá, DC, Colombia., Vallejo MT; Clinical and Epidemiologic Cancer Research Group, Instituto Nacional de Cancerología, Bogotá, DC, Colombia.
Jazyk: angličtina
Zdroj: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery [Clin Otolaryngol] 2024 Mar; Vol. 49 (2), pp. 270-276. Date of Electronic Publication: 2023 Nov 29.
DOI: 10.1111/coa.14126
Abstrakt: Objectives: We aimed to determine the radioguided occult lesion localization (ROLL) reliability in the reoperation of patients with differentiated thyroid cancer (DTC) and persistent or recurrent non-palpable loco-regional disease who underwent surgery at the Instituto Nacional de Cancerología between 2012 and 2021.
Design: Observational retrospective cohort study.
Participants: We included data from patients with DTC that underwent resection with ROLL.
Main Outcome Measures: Reliability analysed as percentage of patients with complete resection of tumour lesion using ROLL, disease-free survival, second loco-regional relapse, adequate resectability and complications.
Results: Two hundred and four cases were obtained. Pathological examination revealed papillary thyroid carcinoma in 202 patients, and follicular thyroid carcinoma in 2. Reliability was 96.57% in patients who underwent ROLL. When wide resection was performed-at surgeon's discretion-the reliability increased to 97.5%.
Conclusions: The high reliability obtained suggests that ROLL was effective to localize non-palpable relapsing lesions. To our knowledge, this is the largest sample size published on this topic to date.
(© 2023 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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