Pterygoid Muscle Necrosis Caused by Radiation and Intra-Arterial Cisplatin Infusion Chemotherapy (RADPLAT): A Case Report.

Autor: Miyamoto K; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Sato M; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Koike S; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Kimura T; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Abe D; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Wakasaki T; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Kitano M; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan., Yasumatsu R; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.
Jazyk: angličtina
Zdroj: Case reports in oncology [Case Rep Oncol] 2023 Nov 24; Vol. 16 (1), pp. 1475-1481. Date of Electronic Publication: 2023 Nov 24 (Print Publication: 2023).
DOI: 10.1159/000534939
Abstrakt: Introduction: Radiation and intra-arterial cisplatin infusion chemotherapy (RADPLAT) for advanced maxillary sinus cancer has accumulated evidence as a treatment with fewer complications and better 5-year survival rates. In this study, we report a case in which pterygoid muscle necrosis occurred 6 months following RADPLAT treatment for maxillary sinus cancer.
Case Presentation: The 45-year-old woman had a long history of taking immunosuppressants against rheumatoid arthritis (RA) prior to treatment. Although achieving complete response (CR) to RADPLAT, the patient developed trismus (1 fingerbreadth or less) 6 months following treatment. Abscess formation and recurrence were suspected from the imaging findings; however, the biopsy with endoscopy indicated necrotic tissue. Currently, 18 months have passed without cancer recurrence. Although trismus temporarily improved with rehabilitation, the width of the mouth opening is currently a few millimeters, so the patient can only take liquid food.
Conclusion: Pterygoid muscle necrosis should be recognized as a new major complication.
Competing Interests: The authors have no conflicts of interest to declare.
(© 2023 The Author(s). Published by S. Karger AG, Basel.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje