Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania.

Autor: Kajeguka DC; Kilimanjaro Christian Medical University College, Moshi, Tanzania., Mponela FM; Kilimanjaro Christian Medical University College, Moshi, Tanzania., Mkumbo E; Kilimanjaro Christian Medical University College, Moshi, Tanzania., Kaaya AN; Kilimanjaro Christian Medical University College, Moshi, Tanzania., Lasway D; Kilimanjaro Christian Medical University College, Moshi, Tanzania., Kaaya RD; Kilimanjaro Christian Medical University College, Moshi, Tanzania.; Pan-African Malaria Vector Control Consortium, Moshi, Tanzania., Alifrangis M; Centre for Medical Parasitology, Department Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Elanga-Ndille E; Centre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon., Mmbaga BT; Kilimanjaro Christian Medical University College, Moshi, Tanzania.; Kilimanjaro Clinical Research Institute, Moshi, Tanzania., Kavishe R; Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Jazyk: angličtina
Zdroj: Journal of tropical medicine [J Trop Med] 2023 Nov 08; Vol. 2023, pp. 5576300. Date of Electronic Publication: 2023 Nov 08 (Print Publication: 2023).
DOI: 10.1155/2023/5576300
Abstrakt: Dengue virus is among the most important re-emerging arbovirus that causes global public health attention. Dengue has historically been thought of as an urban disease that frequently occurs in rapidly urbanized settings. However, dengue has become more widespread in rural regions in recent years. Understanding the changing dengue epidemiology in different geographical settings is important for targeted intervention. In Tanzania, dengue fever is not frequently reported because of the poor surveillance infrastructure, underestimation, and a lack of consideration of dengue as a priority. Therefore, the true burden as well as the risk factors for increased transmission has not been fully ascertained, particularly in rural areas. A cross-sectional community-based study was conducted in June 2021, involving a total of 362 participants of all age groups. We investigated the prevalence of acute dengue infection, seroprevalence, and associated factors among the community in three villages of the rural Handeni district. The prevalence of acute dengue infection (based on PCR) was 2.2% (8/362). Dengue-specific IgM and IgG antibodies were detected in 3.3% (12/362) and 5.2% (19/362) of the participants, respectively. Adult participants who were having vegetation around their houses were more likely to be DENV seropositive (AOR = 2.4, CI = 1.88-4.18, p value = 0.05). Children living in houses with garbage pit around their households were less likely to be DENV seropositive (AOR = 0.13, CI = 0.03-0.56, p value <0.01). DENV continues to circulate in rural Tanzania, causes an alarming situation, and necessitates prompt public health action to enhance vector surveillance and control in rural communities.
Competing Interests: The authors declare that there are no conflicts of interest.
(Copyright © 2023 Debora C. Kajeguka et al.)
Databáze: MEDLINE
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