Embolic Phenomena of Libman-Sacks Endocarditis and Antiphospholipid Syndrome.

Autor:	Gorantla A; Cardiology, State University of New York (SUNY) Downstate HSC, Brooklyn, USA., Schaible M; Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA., Sivakumar SS; Neurology, State University of New York Downstate Health Sciences University, Brooklyn, USA., Kishore A; Internal Medicine, Sisters of Charity Hospital, Buffalo, USA., Andrew-Palmer W; Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA., Unal S; Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA., Ramirez M; Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA., Panduranga V; Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA., Budzikowski AS; Division of Cardiovascular Medicine - Electrophysiology section, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Oct 13; Vol. 15 (10), pp. e46957. Date of Electronic Publication: 2023 Oct 13 (Print Publication: 2023).
DOI:	10.7759/cureus.46957
Abstrakt:	Patients with systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APS) are at high risk of developing arterial or venous thromboembolism and a state of systemic hypercoagulability. Libman-Sacks endocarditis (LSE) is a type of non-bacterial endocarditis usually seen in patients with systemic lupus erythematosus and antiphospholipid antibody syndrome. These vegetations dislodge easily and can cause profound neurological and systemic complications in the form of emboli. We describe one such case of a young woman with known SLE who presented with an acute middle cerebral artery (MCA) stroke and was found to have APS with extensive mitral valve vegetation, indicating Libman-Sacks endocarditis on echocardiography. Recognizing the increasing frequency of both APS and LSE in patients with SLE and screening patients, especially the younger population with SLE, for APS is vital. Furthermore, in those patients presenting with embolic events, echocardiography plays a key role as it can help expedite the diagnosis of LSE. Our case report also reiterates that warfarin, when compared to direct oral anticoagulants (DOAC), is superior in decreasing future embolic events. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Gorantla et al.)
Databáze:	MEDLINE
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