Rare Loxoscelism-Associated IgG Coombs-Positive Hemolytic Anemia Treated Successfully With Systemic Corticosteroids.

Autor:	Alqam A; Department of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA., Zakhour J; Department of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA., Karam W; Department of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA., Maldonado G; Department of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA., Reddy PS; Department of Hematology and Oncology, University of Kansas School of Medicine-Wichita, Wichita, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Oct 21; Vol. 15 (10), pp. e47424. Date of Electronic Publication: 2023 Oct 21 (Print Publication: 2023).
DOI:	10.7759/cureus.47424
Abstrakt:	Loxoscelism-associated hemolytic anemia is a rare but critical complication of brown recluse spider bites. It may lead to various systemic manifestations, including jaundice, dark urine, and anemia-related symptoms, in addition to general loxoscelism symptoms such as skin lesions, fever, myalgia, nausea, and vomiting. Prompt diagnosis is crucial and requires recognizing typical laboratory findings such as low hemoglobin, elevated lactate dehydrogenase, reduced haptoglobin levels, and possibly a positive direct antiglobulin test. There is no definitive guideline for the treatment of loxoscelism-associated hemolytic anemia. we report a case of a 32-year-old female who developed severe Coombs-positive autoimmune hemolytic anemia following a brown recluse spider bite, with an improvement in hemoglobin levels and hemolysis indices after the administration of systemic corticosteroids. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Alqam et al.)
Databáze:	MEDLINE
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