Hyperlipasemia Sans Pancreatitis: A Case Series.
| Autor: | George J; Internal Medicine, Employees State Insurance Corporation (ESIC) Medical College & Post-Graduate Institute of Medical Sciences and Research (PGIMSR), Chennai, IND., Gnanamoorthy K; Internal Medicine, SRM Medical College, Kattankulathur, IND., Suthakaran PK; Internal Medicine, Saveetha Medical College Hospital, Saveetha Institute of Medical And Technical Sciences (SIMATS), Kanchipuram, IND., Baliga KV; Nephrology, Employees State Insurance Corporation (ESIC) Medical College & Post-Graduate Institute of Medical Sciences and Research (PGIMSR), Chennai, IND. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Oct 27; Vol. 15 (10), pp. e47781. Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.47781 |
| Abstrakt: | Acute pancreatitis results in inflammation and autodigestion of pancreatic acinar cells leading to the elevation of pancreatic enzymes, namely, amylase and lipase. Serum lipase levels have long been considered a hallmark of acute pancreatitis. However, pancreatitis is not always the cause of elevated serum lipase levels. This series presents four patients who had elevated serum lipase levels without any demonstrable damage to the pancreas on imaging. On further evaluation, one of the patients was found to have acute on chronic kidney disease (CKD) whose lipase levels settled later. A patient presenting with an episode of acute gastroenteritis, later diagnosed to have Crohn's disease, also had hyperlipasemia, which improved after a course of initial antibiotics. Non-gastrointestinal causes, such as lupus nephritis and organophosphate (OP) poisoning, also had elevated lipase levels on presentation, in which the hyperlipasemia settled with supportive treatments. It is important to remember other causes of elevated lipase levels in patients with a normal pancreas on imaging studies. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, George et al.) |
| Databáze: | MEDLINE |
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