Primary Spinal Intradural Extramedullary Ewing's Sarcoma/Peripheral Neuroectodermal Tumour Masquerading Clinically as a Neurogenic Tumour: A Case Report and Review of Literature.

Autor: Praveen BK; Department of Pathology and Lab Medicine, All India Institute of Medical Science Bhopal, Saket Nagar, Habib Ganj, Bhopal, Madya Pradesh, India., Das S; Department of Radiotherapy, All India Institute of Medical Science Bhopal, Saket Nagar, Habib Ganj, Bhopal, Madya Pradesh, India., Gupta M; Department of Radiotherapy, All India Institute of Medical Science Bhopal, Saket Nagar, Habib Ganj, Bhopal, Madya Pradesh, India., Joshi D; Department of Pathology and Lab Medicine, All India Institute of Medical Science Bhopal, Saket Nagar, Habib Ganj, Bhopal, Madya Pradesh, India., Panwar H; Department of Pathology and Lab Medicine, All India Institute of Medical Science Bhopal, Saket Nagar, Habib Ganj, Bhopal, Madya Pradesh, India.
Jazyk: angličtina
Zdroj: Annals of neurosciences [Ann Neurosci] 2023 Oct; Vol. 30 (4), pp. 251-255. Date of Electronic Publication: 2023 Sep 14.
DOI: 10.1177/09727531231190979
Abstrakt: Ewing's Sarcomas (ES)/Peripheral neuroectodermal tumour (pPNET) are heterogenous group of rare, highly malignant, undifferentiated primitive round-cell neoplasms of neuroectodermal origin. pPNETs are seldom observed to involve the spine of which Spinal Intradural Extramedullary Extraosseous Primary ES/pPNET are extremely rare. We report a case of a 23-year-old male with complaints of low backache and hip pain radiating to the left inguinal region for four months. Radiology findings were suggestive of a neurogenic tumour. Cytomorphology, histomorphology and immunohistochemistry evaluation were done. Diagnosis was consistent with ES/pPNET. Careful correlation between clinical history, cytomorphology, histopathology, immunohistochemical and molecular analysis can help to distinguish primary spinal ES/PNET from other primary spinal tumours and will help clinicians to start treatment at the earliest.
Competing Interests: The authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.
(© The Author(s) 2023.)
Databáze: MEDLINE
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