Combining COVID-19 and seasonal influenza vaccines together to increase the acceptance of newly developed vaccines in the Eastern Mediterranean Region: a cross-sectional study.

Autor:	Hussein MF; Occupational Health and Industrial Medicine Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt., Elshabrawy A; Biostatistics and Demography Department, Faculty of Graduate Studies for Statistical Research, Cairo University, Giza, Egypt., Ibrahim SA; Biostatistics and Demography Department, Faculty of Graduate Studies for Statistical Research, Cairo University, Giza, Egypt., Abdel-Rahman S; Biostatistics and Demography Department, Faculty of Graduate Studies for Statistical Research, Cairo University, Giza, Egypt., Shiba HAA; Public Health and Community Medicine at Faculty of Medicine (Girls), Al-Azhar University, Cairo, Egypt., Elrewany E; Tropical Health Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt., Haroon Hairan M; Department of Natural Resources Management, Faculty of Environment, Kabul University, Kabul, Afghanistan., Ghazy RM; Tropical Health Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
Jazyk:	angličtina
Zdroj:	Annals of medicine [Ann Med] 2023; Vol. 55 (2), pp. 2286339. Date of Electronic Publication: 2023 Nov 29.
DOI:	10.1080/07853890.2023.2286339
Abstrakt:	Background and Aim: The World Health Organization (WHO) recommended the concomitant administration (co-administration) of inactivated seasonal influenza and coronavirus disease 2019 (COVID-19) vaccines, encouraging the practice for the 2021-2022 flu season. This study aimed to assess the acceptance of simultaneously receiving the seasonal influenza vaccine (SIV) and the COVID-19 vaccine in a single administration to reduce vaccine rejection towards the COVID-19 vaccination. Methods: An online-based cross-section survey was conducted from 1 September to 9 November 2022, in the Eastern Mediterranean Region (EMR) through distributing the survey on different social media platforms, including Facebook, Twitter, LinkedIn and WhatsApp. We used the multi-level model to assess the variation of vaccine countries across EMR countries. Results: In total, 3300 participants were included in this survey from 11 countries distributed in the EMR. More than one-third (40.7%) were aged 18-25 years, 60.6% were females, 54.0% had a university degree, 43.1% had previous COVID-19, and 41.9% had relatives or friends who died from COVID-19. In total, 43.3% accepted this combination because it is less costly (9%), safer (18%), more effective (17%), and has fewer doses (19%). Rejection of this combination was due to fear of side effects (31%), and no studies have been published on their effects (31%). There was a significant difference across countries, which accounted for 6% of the variance in the log-odds of accepting the combined vaccination. Multi-level analysis revealed that being male, African and losing a family member or friend from COVID-19 increased the acceptance of the theoretical combined vaccines. Additionally, the number of doses taken of the COVID-19 and influenza vaccines separately significantly affected the combined vaccine acceptance. However, previous COVID-19 infection and older age reduced the odds of accepting the combined vaccines. Occupational level, social status and educational level didn't significantly affect the acceptance odds. Conclusions: We can conclude that combining SIV and COVID-19 vaccines in one shot increased the overall acceptance of COVID-19 vaccines among vaccine rejectors.
Databáze:	MEDLINE
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