The role of lipid droplet associated proteins in inherited human disorders.

Autor: Duan X; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, CB2 0QQ, UK., Savage DB; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, CB2 0QQ, UK.
Jazyk: angličtina
Zdroj: FEBS letters [FEBS Lett] 2024 May; Vol. 598 (10), pp. 1205-1206. Date of Electronic Publication: 2023 Dec 14.
DOI: 10.1002/1873-3468.14779
Abstrakt: Proteins which associate with the surface of lipid droplets are intimately involved in the regulation of the droplets. Several human inherited disorders have now been linked to loss- and, in some cases, likely gain-of-function mutations in the genes encoding these proteins. These are summarised in this Graphical Review.
(© 2023 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.)
Databáze: MEDLINE
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