The clinical epidemiology, management, and outcomes of patients diagnosed with encephalitis in North Carolina, 2015-2020.

Autor: Fellner A; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., White S; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Rockwell E; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Giandomenico D; Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Diaz MM; Department of Neurology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Weber DJ; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA.; Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Miller MB; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA., Boyce RM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA.; Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA.; Carolina Population Center, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina, USA.
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2023 Dec 19; Vol. 61 (12), pp. e0073123. Date of Electronic Publication: 2023 Nov 28.
DOI: 10.1128/jcm.00731-23
Abstrakt: Importance: Despite the relatively high mortality and the difficulty in diagnosis, nearly one-third of patients hospitalized with a documented diagnosis of encephalitis did not undergo a lumbar puncture (LP). When an LP was performed, pathogen-specific testing was greatly underutilized. Infectious etiologies were most common, but over 40% of cases were idiopathic at discharge. These findings suggest that there is a substantial opportunity to improve the quality of care through more accurate and timely diagnosis.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE