Bis-chalcone Fluorescent Probe for Hydrazine Ratio Sensing in Environment and Organism.

Autor: Yang YS; School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou, 730050, China. yangyunshang@tom.com., Wang FN; School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou, 730050, China., Zhang YP; School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou, 730050, China. yingpengzhang@126.com., Liang YN; School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou, 730050, China., Xue JJ; State Key Laboratory of Applied Organic Chemistry & College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China.
Jazyk: angličtina
Zdroj: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2024 Aug; Vol. 196 (8), pp. 5064-5079. Date of Electronic Publication: 2023 Nov 28.
DOI: 10.1007/s12010-023-04785-3
Abstrakt: In this paper, four novel hydrazine fluorescent probes X 1 -X 4 with bis-chalcone structure were designed and synthesized. Through the measurement of its optical properties, it is found that it can quickly identify hydrazine, high sensitivity, low detection limit, and good anti-interference ability. The recognition of hydrazine by probes X 1 -X 4 is not affected in the pH range of 4-10, X 2 has the highest sensitivity, and the detection limit is as low as 0.336 × 10 -7 M. Through Gaussian quantization calculation of probe molecules and their reaction products with hydrazine, it is speculated that the recognition mechanism is the closure of intramolecular charge transfer effect. In addition, the cytotoxicity and imaging of HeLa cells were tested, which showed that probes X 1 -X 4 could be used to detect hydrazine in cells.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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