Lymphangioleiomyomatosis Showing the Development of Mycobacterium abscessus subsp. massiliense Infection during Sirolimus Therapy.
| Autor: | Yanagisawa A; Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Takimoto T; Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Kurahara Y; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Tsuyuguchi K; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Yoshida S; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Hirose M; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan., Inoue Y; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan.; Department of Internal Medicine, Osaka Anti-Tuberculosis Association Osaka Fukujuji Hospital, Japan., Arai T; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan. |
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| Jazyk: | angličtina |
| Zdroj: | Internal medicine (Tokyo, Japan) [Intern Med] 2024 Jul 15; Vol. 63 (14), pp. 2043-2047. Date of Electronic Publication: 2023 Nov 27. |
| DOI: | 10.2169/internalmedicine.2847-23 |
| Abstrakt: | Among nontuberculous mycobacterial pulmonary diseases (NTM-PDs), Mycobacterium abscessus species pulmonary disease (MABS-PD) is one of the most severe and intractable infections. We herein report a 45-year-old woman with advanced lymphangioleiomyomatosis (LAM) who developed MABS-PD while undergoing sirolimus therapy. MABS-PD was immediately controlled using antibiotic therapy, although the patient's lung transplant registration was significantly delayed. To our knowledge, this is the first case report on the development of NTM-PD in a patient with LAM before lung transplantation. This case suggests that the early diagnosis and optimal treatment of NTM-PD are crucial in patients with advanced LAM. |
| Databáze: | MEDLINE |
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