Kinetic Modeling Methods in Preclinical Positron Emission Tomography Imaging.

Autor: Knyzeliene A; Queen's Medical Research Institute, Edinburgh, UK., Shaw R; Queen's Medical Research Institute, Edinburgh, UK., Balogh V; Queen's Medical Research Institute, Edinburgh, UK., Tavares AAS; Queen's Medical Research Institute, Edinburgh, UK. adriana.tavares@ed.ac.uk.
Jazyk: angličtina
Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2729, pp. 441-455.
DOI: 10.1007/978-1-0716-3499-8_25
Abstrakt: There is an expanding number of applications for preclinical positron emission tomography (PET) imaging. Kinetic modeling of PET data provides rich multiparameter information on radiotracer uptake and binding in tissue from a single experiment. In this chapter, we provide a practical step-by-step protocol to assist with collection of PET data for kinetic modeling studies in rats and mice.
(© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE