| Autor: |
Slabu AI; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry of the Romanian Academy, 202 B Spl. Independenței, S6, 060023 Bucharest, Romania.; Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania., Miu L; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry of the Romanian Academy, 202 B Spl. Independenței, S6, 060023 Bucharest, Romania.; Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania., Ghibu E; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry of the Romanian Academy, 202 B Spl. Independenței, S6, 060023 Bucharest, Romania.; Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania., Stavarache CE; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry of the Romanian Academy, 202 B Spl. Independenței, S6, 060023 Bucharest, Romania.; Advanced Polymer Materials Group, National University of Science and Technology Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania., Stan R; Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania., Teodorescu F; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry of the Romanian Academy, 202 B Spl. Independenței, S6, 060023 Bucharest, Romania. |
| Abstrakt: |
We reported the tunable synthesis of new vegetable oil-UV filter bioconjugates using sea buckthorn oil (SBO) and p -methoxycinnamic acid ( p -MCA) as an alternative to the common UV filter, ethylhexyl- p -methoxycinnamate (octinoxate). The synthetic strategy is based on the sustainable ring-opening reaction of epoxidized SBO with p -MCA in heterogenous catalysis in eco-friendly solvents. The amount of UV-absorptive moieties grafted on the triglyceride backbone is controlled by different epoxidation degrees as determined by NMR spectroscopy. The performance of the new UV-absorber bioconjugates was assessed by in vitro sun protection factor (SPF) measurements after inclusion in SBO-ethylcellulose (EC) oleogels and comparison with the SPF value of the SBO-EC-octinoxate oleogel with equivalent p -MCA acid moieties (10% wt/wt). The concentration obtained for the SBO-EC oleogel formulated with the bioconjugate with the lowest degree of functionalization, namely 55%, represents 45% of the SPF determined for the SBO-EC-octinoxate oleogel, regardless of the concentration of measured solutions. The new concept of vegetable oil-UV-absorber bioconjugates has potential UV-B photoprotective properties when included in oleogel formulations and deserves further investigation of their properties and stability including association with UV-A absorbers, respectively. |
