The essential oil of Kochia scoparia (L.) Schrad. as a potential repellent against stored-product insects.

Autor: Wang Y; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, Jiangsu, China. wangyangjs@mail.bnu.edu.cn.; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China. wangyangjs@mail.bnu.edu.cn., Bian XK; Department of Pharmacy, Yancheng No.1 People's Hospital, Yancheng, 224000, Jiangsu, China., Zhang L; Department of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, 215000, Jiangsu, China., Chen WY; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, Jiangsu, China., Lyu QJ; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, Jiangsu, China., Du SS; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2023 Dec; Vol. 30 (59), pp. 124416-124424. Date of Electronic Publication: 2023 Nov 23.
DOI: 10.1007/s11356-023-31011-8
Abstrakt: Chemical composition of the essential oil from Kochia scoparia (L.) Schrad. (syn. Bassia scoparia (L.) A. J. Scott) was analyzed in quality and quantity by GC-MS and GC-FID. Repellent activities of the essential oil from K. scoparia (KSEO) were evaluated against two common species of stored-product insects Tribolium castaneum Herbst and Liposcelis bostrychophila Badonnel. Results indicated that KSEO mainly consisted of eugenol, β-caryophyllene, and α-humulene, accounting for 75.6%, 8.2%, and 1.4% of the total oil, respectively. KSEO and the three major components were repellent to T. castaneum and L. bostrychophila adults. Notably, KSEO exerted significant effects, comparable to the positive control DEET at 2 and 4 h post-exposure. Eugenol at 63.17-2.53 nL/cm 2 exhibited high percentage repellency ranging from 96 to 70% against L. bostrychophila during 4-h exposure. To gain further insights into the repellent activity, molecular docking simulation was performed with eugenol as the ligand and an odorant binding protein TcOBPC12 (gene: TcOBP10B) from the model insect T. castaneum as the receptor. Docking calculation results revealed that TcOBPC12 had binding affinity to eugenol (△G =  - 4.52 kcal/mol) along with a hydrogen bond of 0.18 nm (1.8 Å) long forming between them, which could be an important target protein associated with identifying volatile repellent molecules. This work highlights the promising potential of KSEO as a botanical repellent for controlling stored-product insects.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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