A dynamic sequence of visual processing initiated by gaze shifts.

Autor: Parker PRL; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA.; Behavioral and Systems Neuroscience, Department of Psychology, Rutgers University, New Brunswick, NJ, USA., Martins DM; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA., Leonard ESP; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA., Casey NM; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA., Sharp SL; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA., Abe ETT; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA., Smear MC; Institute of Neuroscience and Department of Psychology, University of Oregon, Eugene, OR, USA., Yates JL; Department of Biology and Program in Neuroscience and Cognitive Science, University of Maryland, College Park, MD, USA.; Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, CA, USA., Mitchell JF; Department of Brain and Cognitive Sciences and Center for Visual Sciences, University of Rochester, Rochester, NY, USA. jmitchell@bcs.rochester.edu., Niell CM; Institute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR, USA. cniell@uoregon.edu.
Jazyk: angličtina
Zdroj: Nature neuroscience [Nat Neurosci] 2023 Dec; Vol. 26 (12), pp. 2192-2202. Date of Electronic Publication: 2023 Nov 23.
DOI: 10.1038/s41593-023-01481-7
Abstrakt: Animals move their head and eyes as they explore the visual scene. Neural correlates of these movements have been found in rodent primary visual cortex (V1), but their sources and computational roles are unclear. We addressed this by combining head and eye movement measurements with neural recordings in freely moving mice. V1 neurons responded primarily to gaze shifts, where head movements are accompanied by saccadic eye movements, rather than to head movements where compensatory eye movements stabilize gaze. A variety of activity patterns followed gaze shifts and together these formed a temporal sequence that was absent in darkness. Gaze-shift responses resembled those evoked by sequentially flashed stimuli, suggesting a large component corresponds to onset of new visual input. Notably, neurons responded in a sequence that matches their spatial frequency bias, consistent with coarse-to-fine processing. Recordings in freely gazing marmosets revealed a similar sequence following saccades, also aligned to spatial frequency preference. Our results demonstrate that active vision in both mice and marmosets consists of a dynamic temporal sequence of neural activity associated with visual sampling.
(© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.)
Databáze: MEDLINE
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