Functionalized heteroatom-doped carbon dots for biomedical applications: A review.

Autor: Redondo-Fernandez G; Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, 33006, Oviedo, Spain., Cigales Canga J; Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, 33006, Oviedo, Spain., Soldado A; Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, 33006, Oviedo, Spain., Ruiz Encinar J; Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, 33006, Oviedo, Spain. Electronic address: ruizjorge@uniovi.es., Costa-Fernandez JM; Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, 33006, Oviedo, Spain. Electronic address: jcostafe@uniovi.es.
Jazyk: angličtina
Zdroj: Analytica chimica acta [Anal Chim Acta] 2023 Dec 15; Vol. 1284, pp. 341874. Date of Electronic Publication: 2023 Oct 09.
DOI: 10.1016/j.aca.2023.341874
Abstrakt: Carbon nanoparticles (CDs) have recently drawn a great attention in (bio)chemical analysis, sensing and bioimaging owing to their photostability, water stability, minimal toxicity, biocompatibility and ease of surface functionalization. While the vast majority of CDs applications rely on exploiting their fluorescent properties, doping such nanomaterials with various elements has recently received increasing attention as an effective approach to modify their optoelectronic characteristics, introducing novel improved optical features such as phosphorescence, upconversion luminescence or multimodal imaging capabilities. This review article focuses in the recent advances on the synthesis of heteroatom-doped CDs, exhibiting distinctive features of high value for sensing and imaging, as well as various functionalization schemes developed for guided analyte labeling. Relevant applications in chemical sensing, bioimaging and disease therapy are here presented. A final section intends to provide an overview towards future developments of such emerging light-emitting nanomaterials in the design of future devices and strategies for (bio)analytical chemistry.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors declare no conflict of interest.Jose M Costa-Fernandez reports financial support was provided by Gobierno del Principado de Asturias Consejería de Ciencia, Innovación y Universidad. Guillermo Redondo-Fernandez reports financial support was provided by Government of Principality of Asturias. Jorge Ruiz Encinar reports financial support was provided by Spain Ministry of Science and Innovation. Ana Soldado reports financial support was provided by Spain Ministry of Science and Innovation.
(Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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