House dust mite allergy in Malaysia: review of research gaps in the current scenario and the way forward.

Autor: Lee YZ; Office of Postgraduate Studies, UCSI University, 56000, Kuala Lumpur, Malaysia., Kow ASF; Faculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia., Jacquet A; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Alain.J@chula.ac.th., Lee MT; Faculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia.; Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.; Centre of Research for Mental Health and Wellbeing, UCSI University, 56000, Kuala Lumpur, Malaysia., Tham CL; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Malaysia. chauling@upm.edu.my.; Natural Medicines and Products Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. chauling@upm.edu.my.
Jazyk: angličtina
Zdroj: Experimental & applied acarology [Exp Appl Acarol] 2023 Dec; Vol. 91 (4), pp. 509-539. Date of Electronic Publication: 2023 Nov 23.
DOI: 10.1007/s10493-023-00857-5
Abstrakt: The prevalence of house dust mite (HDM) allergy, especially in Asian countries with rapid urbanization, has been increasing. House dust mites thrive in places with relatively high humidity. With the combination of climate change, naturally high humidity, and urbanization, tropical countries like Malaysia are becoming a hotspot for HDM allergy fast. With a previously reported sensitization rate of between 60 and 80%, it is a worrying trend for Malaysia. However, due to incomplete and out-of-date data, as seen by the limited study coverage in the past, these numbers do not paint a complete picture of the true HDM allergy scene in Malaysia. This review briefly discusses the HDM fauna, the HDM sensitization rate, the common diagnosis and therapeutic tools for HDM allergy in Malaysia, and makes suggestions for possible improvements in the future. This review also highlights the need of more comprehensive population-based prevalence studies to be done in Malaysia, encompassing the three main HDMs-Dermatophagoides pteronyssinus, Dermatophagoides farinae, and Blomia tropicalis-as the lack of up-to-date studies failed to give a clearer picture on the current scenario of HDM allergy in Malaysia. Future studies will be beneficial to the nation in preparing a better blueprint for the management and treatment of HDM allergy.
(© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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