Phylogenetic comparative analysis of the cerebello-cerebral system in 34 species highlights primate-general expansion of cerebellar crura I-II.

Autor: Magielse N; Institute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Center Jülich, Wilhelm-Johnen-Straße, 52428, Jülich, Germany. n.magielse@fz-juelich.de.; Otto Hahn Cognitive Neurogenetics Group, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstraße 1A, 04103, Leipzig, Germany. n.magielse@fz-juelich.de.; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. n.magielse@fz-juelich.de., Toro R; Institut Pasteur, Unité de Neuroanatomie Appliquée et Théorique, Université Paris Cité, 25 rue du Dr. Roux, 75724, Paris, France., Steigauf V; Department of Biology, Northern Michigan University, 1401 Presque Isle Ave, MI, 49855, Marquette, USA., Abbaspour M; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Luisenstraße 56, Haus 1, 10117, Berlin, Germany.; Department of Neurology, Charité - Universitätsmedizin Berlin, Bonhoefferweg 3, 10117, Berlin, Germany., Eickhoff SB; Institute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Center Jülich, Wilhelm-Johnen-Straße, 52428, Jülich, Germany.; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany., Heuer K; Institut Pasteur, Unité de Neuroanatomie Appliquée et Théorique, Université Paris Cité, 25 rue du Dr. Roux, 75724, Paris, France.; Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstraße 1A, 04103, Leipzig, Germany., Valk SL; Institute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Center Jülich, Wilhelm-Johnen-Straße, 52428, Jülich, Germany. s.valk@fz-juelich.de.; Otto Hahn Cognitive Neurogenetics Group, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstraße 1A, 04103, Leipzig, Germany. s.valk@fz-juelich.de.; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. s.valk@fz-juelich.de.
Jazyk: angličtina
Zdroj: Communications biology [Commun Biol] 2023 Nov 22; Vol. 6 (1), pp. 1188. Date of Electronic Publication: 2023 Nov 22.
DOI: 10.1038/s42003-023-05553-z
Abstrakt: The reciprocal connections between the cerebellum and the cerebrum have been suggested to simultaneously play a role in brain size increase and to support a broad array of brain functions in primates. The cerebello-cerebral system has undergone marked functionally relevant reorganization. In particular, the lateral cerebellar lobules crura I-II (the ansiform) have been suggested to be expanded in hominoids. Here, we manually segmented 63 cerebella (34 primate species; 9 infraorders) and 30 ansiforms (13 species; 8 infraorders) to understand how their volumes have evolved over the primate lineage. Together, our analyses support proportional cerebellar-cerebral scaling, whereas ansiforms have expanded faster than the cerebellum and cerebrum. We did not find different scaling between strepsirrhines and haplorhines, nor between apes and non-apes. In sum, our study shows primate-general structural reorganization of the ansiform, relative to the cerebello-cerebral system, which is relevant for specialized brain functions in an evolutionary context.
(© 2023. The Author(s).)
Databáze: MEDLINE
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