Antimicrobial and Antifouling Effects of Petal-Like Nanostructure by Evaporation-Induced Self-Assembly for Personal Protective Equipment.

Autor: Lee DU; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea., Jeong SB; Indoor Environment Center, Korea Testing Laboratory, Seoul, 08389, Republic of Korea.; Department of Mechanical Engineering, Sejong University, Seoul, 05006, Republic of Korea., Lee BJ; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea.; School of Mechanical Engineering, Kyungpook National University, Daegu, 41566, Republic of Korea., Park SK; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea., Kim HM; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea., Shin JH; Department of Mechanical Engineering, Sejong University, Seoul, 05006, Republic of Korea., Lee SY; Department of Mechanical Engineering, Sejong University, Seoul, 05006, Republic of Korea., Kim G; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea., Park J; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea., Kim GM; School of Mechanical Engineering, Kyungpook National University, Daegu, 41566, Republic of Korea., Jung JH; Department of Mechanical Engineering, Sejong University, Seoul, 05006, Republic of Korea., Choi DY; Biomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon, 38822, Republic of Korea.
Jazyk: angličtina
Zdroj: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Apr; Vol. 20 (14), pp. e2306324. Date of Electronic Publication: 2023 Nov 21.
DOI: 10.1002/smll.202306324
Abstrakt: Although the personal protective equipment (PPE) used by healthcare workers (HCWs) effectively blocks hazardous substances and pathogens, it does not fully rule out the possibility of infection, as pathogens surviving on the fabric surface pose a substantial risk of cross-infection through unintended means. Therefore, PPE materials that exhibit effective biocidal activity while minimizing contamination by viscous body fluids (e.g., blood and saliva) and pathogen-laden droplets are highly sought. In this study, petal-like nanostructures (PNSs) are synthesized through the vertical rearrangement of colloidal lamellar bilayers via evaporation-induced self-assembly of octadecylamine, silica-alumina sol, and diverse photosensitizer. The developed method is compatible with various fabrics and imparts visible-light-activated antimicrobial and superhydrophobic-based antifouling activities. PNS-coated fabrics could provide a high level of protection and effectively block pathogen transmission as exemplified by their ability to roll off viscous body fluids reducing bacterial droplet adhesion and to inactivate various microorganisms. The combination of antifouling and photobiocidal activities results in the complete inactivation of sprayed pathogen-laden droplets within 30 min. Thus, this study paves the way for effective contagious disease management and the protection of HCWs in general medical environments, inspiring further research on the fabrication of materials that integrate multiple useful functionalities.
(© 2023 The Authors. Small published by Wiley‐VCH GmbH.)
Databáze: MEDLINE
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