Diagnostic approaches, aetiological agents and their associations with short-term survival and laminitis in horses with acute diarrhoea admitted to referral institutions.

Autor: Gomez DE; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada., Arroyo LG; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada., Schoster A; Vetsuisse Faculty, Equine Department University of Zurich, Zurich, Switzerland.; Ludwig-Maximilians-University Munich, Equine Clinic, Oberschleissheim, Germany., Renaud DL; Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada., Kopper JJ; Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa, USA., Dunkel B; Department of Clinical Science and Services, The Royal Veterinary College, Hertfordshire, UK., Byrne D; College of Veterinary Medicine, Murdoch University, Perth, Western Australia, Australia., Toribio RE; College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Jazyk: angličtina
Zdroj: Equine veterinary journal [Equine Vet J] 2024 Sep; Vol. 56 (5), pp. 959-969. Date of Electronic Publication: 2023 Nov 20.
DOI: 10.1111/evj.14024
Abstrakt: Background: An international description of the diagnostic approaches used in different institutions to diagnose acute equine diarrhoea and the pathogens detected is lacking.
Objectives: To describe the diagnostic approach, aetiological agents, outcome, and development of laminitis for diarrhoeic horses worldwide.
Study Design: Multicentre retrospective case series.
Methods: Information from horses with acute diarrhoea presenting to participating institutions between 2016 and 2020, including diagnostic approaches, pathogens detected and their associations with outcomes, were compared between institutions or geographic regions.
Results: One thousand four hundred and thirty-eight horses from 26 participating institutions from 4 continents were included. Overall, aetiological testing was limited (44% for Salmonella spp., 42% for Neorickettsia risticii [only North America], 40% for Clostridiodes difficile, and 29% for ECoV); however, 13% (81/633) of horses tested positive for Salmonella, 13% (35/262) for N. risticii, 9% (37/422) for ECoV, and 5% (27/578) for C. difficile. C. difficile positive cases had greater odds of non-survival than horses negative for C. difficile (OR: 2.69, 95%CI: 1.23-5.91). In addition, horses that were positive for N. risticii had greater odds of developing laminitis than negative horses (OR: 2.76, 95%CI: 1.12-6.81; p = 0.029).
Main Limitations: Due to the study's retrospective nature, there are missing data.
Conclusions: This study highlighted limited diagnostic investigations in cases of acute equine diarrhoea. Detection rates of pathogens are similar to previous reports. Non-survival and development of laminitis are related to certain detected pathogens.
(© 2023 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.)
Databáze: MEDLINE
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