Mechanical properties of simulated dentin caries treated with metal cations and L-ascorbic acid 2-phosphate.

Autor: Saghiri MA; Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, NJ, USA. saghiri@gmail.com.; Department of Endodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA. saghiri@gmail.com.; MSB C639A, Rutgers Biomedical and Health Sciences, 185 South Orange Avenue, Newark, NJ, 07103, USA. saghiri@gmail.com., Vakhnovetsky J; Sector of Innovation in Dentistry, Dr. Hajar Afsar Lajevardi Research Cluster (DHAL), Hackensack, NJ, USA.; University of Michigan School of Dentistry, Ann Arbor, MI, USA., Abdolmaleki A; Polydent Dental Materials Consulting, Victoria, Canada., Samadi E; Sector of Innovation in Dentistry, Dr. Hajar Afsar Lajevardi Research Cluster (DHAL), Hackensack, NJ, USA.; Biomaterials Laboratory, Rutgers School of Dental Medicine, Newark, NJ, USA., Samadi F; Sector of Innovation in Dentistry, Dr. Hajar Afsar Lajevardi Research Cluster (DHAL), Hackensack, NJ, USA.; Biomaterials Laboratory, Rutgers School of Dental Medicine, Newark, NJ, USA., Napoli S; Department of Oral & Maxillofacial Surgery, Rutgers School of Dental Medicine, Newark, NJ, USA., Conte M; Department of Restorative Dentistry, Office of Clinical Affairs, Rutgers School of Dental Medicine, Newark, NJ, USA., Morgano SM; Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, NJ, USA.
Jazyk: angličtina
Zdroj: Odontology [Odontology] 2024 Apr; Vol. 112 (2), pp. 489-500. Date of Electronic Publication: 2023 Nov 17.
DOI: 10.1007/s10266-023-00868-z
Abstrakt: This pH cycling study aimed to investigate the effects of L-Ascorbic acid 2-phosphate (AA2P) salts of Mg, Zn, Mn, Sr, and Ba on the surface microhardness, compressive strength, diametral tensile strength (DTS), and solubility of root canal dentin. 186 cylindrical dentin specimens from 93 teeth were fortified with optimal concentrations of AA2P salts of Mg (0.18 mM), Zn (5.3 µM), Mn (2.2 × 10 -8  M), Sr (1.8 µM), and Ba (1.9 µM). Saline was used as the control group. These dentin specimens underwent a 3-day cycling process simulating dentin caries formation through repeated sequences of demineralization and remineralization. Surface microhardness at 100 and 500 µm depths (n = 10/subgroup), scanning electron microscopy (n = 3/group), compressive strength (n = 10/group), DTS (n = 6/group), and solubility (n = 5/group) tests were performed to analyze the dentin specimens. Data were analyzed using Kolmogorov-Smirnov, one-way ANOVA, and Post Hoc Tukey tests (p < 0.05). The control group had significantly lower microhardness at both depths (p < 0.001), reduced DTS (p = 0.001), decreased compressive strength (p < 0.001), and higher weight loss (p < 0.001) than all other groups. The Sr group had the highest compressive strength and microhardness among all the groups. The microhardness was significantly higher for the 500 µm depth than the 100 µm depth (p < 0.001), but the difference in microhardness between depths across groups was not significant (p = 0.211). All fortifying solutions provided some protection against artificial caries lesions. Therefore, these elements might have penetrated and reinforced the demineralized dentin against acid dissolution.
(© 2023. The Author(s), under exclusive licence to The Society of The Nippon Dental University.)
Databáze: MEDLINE
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