[Clinical problems in Medical Mycology: Problem number 56].

Autor: Messina F; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina., Marin E; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina., Sansostera A; Unidad de Endoscopía Per Oral, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina., Romero M; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina. Electronic address: mecharomero@gmail.com., Depardo R; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina., Negroni R; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina., Leonel B; Instituto Cardiológico Banfield, Buenos Aires, Argentina., Santiso G; Unidad Micología, Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina.
Jazyk: Spanish; Castilian
Zdroj: Revista iberoamericana de micologia [Rev Iberoam Micol] 2023 Apr-Jul; Vol. 40 (2-3), pp. 35-38. Date of Electronic Publication: 2023 Nov 15.
DOI: 10.1016/j.riam.2022.12.001
Abstrakt: We present the case of a twenty six year-old woman with rheumatoid arthritis, treated with certolizumab. She sought medical attention due to cough, fever and night sweats. X-ray exam showed a miliary pneumonia. She was treated for tuberculosis and 50days later she presented with aphasia. Magnetic nuclear resonance revealed brain lesions. Histoplasma capsulatum PCR test and urinary antigen were positive, so an antifungal treatment with voriconazole was started. Visual adverse effects forced to change the antifungal schedule in both the length of treatment and the antifungal drug. With this measure the patient progressed favorably. The test of urinary Histoplasma capsulatum antigen and PCR amplification were key to make a diagnosis and also for a follow-up.
(Copyright © 2023 Asociación Española de Micología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE