A Hue-Value method for semi-automated assessment of Lid Wiper Epitheliopathy.

Autor: Ravikumar A; The University of Houston College of Optometry, Houston, TX, USA., Queener HM; The University of Houston College of Optometry, Houston, TX, USA., Osae EA; The University of Houston College of Optometry, Houston, TX, USA., Ritchey ER; The University of Houston College of Optometry, Houston, TX, USA. Electronic address: erritche@central.uh.edu.
Jazyk: angličtina
Zdroj: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2024 Feb; Vol. 47 (1), pp. 102090. Date of Electronic Publication: 2023 Nov 17.
DOI: 10.1016/j.clae.2023.102090
Abstrakt: Background: Lid wiper epitheliopathy (LWE) is a marker of an abnormal lid/cornea interaction. This study proposes an automated Hue-Value grading algorithm of LWE staining following manual selection of the region of interest.
Methods: Images of LWE staining were processed using Hue and Value from HSV (Hue-Saturation-Value) color space with a custom MATLAB program. Thirty-one images were successfully analyzed. Examiners analyzed images in random order twice, separated by more than a week. Bland Altman and Intraclass Correlation Coefficients (ICC) were performed.
Results: There was no difference (p > 0.05) between upper (UL) and lower (LL) eyelids for LWE height (UL: 0.12 ± 0.12 mm, LL: 0.12 ± 0.07 mm), width (UL: 10.70 ± 3.84 mm, LL: 10.26 ± 3.49 mm), or area (UL: 2.85 ± 2.67 mm 2 , LL: 2.63 ± 1.71 mm 2 ). There was no between examiner difference for all eyelid LWE height or area (p > 0.05), but a difference in LWE width (0.16 mm; p = 0.031). ICC for LWE height, width and area were 0.996 (95% CI: 0.993 to 0.998), 0.997 (95% CI: 0.992 to 0.998) and 0.999 (95% CI: 0.998 to 0.999). There was no between examiner difference for height or area (p > 0.05) for UL, but a difference in LWE width (0.28 mm; p = 0.026). ICC for height, width and area were 0.999 (95% CI: 0.996 to 1.00), 0.995 (95% CI: 0.982 to 0.999) and 1.00 (95% CI: 0.999 to 1.00). There was no difference in LWE height, width or area for LL (all p > 0.05). ICC were 0.991 (95% CI: 0.973 to 0.997) for height, 0.998 (95% CI: 0.995 to 0.999) for width and 0.997 (95% CI: 0.990 to 0.999) for area.
Conclusions: This novel method results in highly repeatable interexaminer measures of LWE staining after general lid region delineation. Small differences in LWE width were observed between examiners.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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