From the organ bath to the whole person: a review of human colonic motility.

Autor: Wattchow DA; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.; Departments of Surgery and Gastroenterology, Flinders Medical Centre, Adelaide, South Australia, Australia., Brookes SJ; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Spencer NJ; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Heitmann PT; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., De Giorgio R; Department of Translational Medicine, University of Ferrara, Ferrara, Italy., Costa M; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Dinning PG; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.; Departments of Surgery and Gastroenterology, Flinders Medical Centre, Adelaide, South Australia, Australia.
Jazyk: angličtina
Zdroj: ANZ journal of surgery [ANZ J Surg] 2024 Mar; Vol. 94 (3), pp. 320-326. Date of Electronic Publication: 2023 Nov 16.
DOI: 10.1111/ans.18779
Abstrakt: Motor function of the colon is essential for health. Our current understanding of the mechanisms that underlie colonic motility are based upon a range of experimental techniques, including molecular biology, single cell studies, recordings from muscle strips, analysis of part or whole organ ex vivo through to in vivo human recordings. For the surgeon involved in the clinical management of colonic conditions this amounts to a formidable volume of material. Here, we synthesize the key findings from these various experimental approaches so that surgeons can be better armed to deal with the complexities of the colon.
(© 2023 The Authors. ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons.)
Databáze: MEDLINE
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