High prevalence of TB multimorbidity among adults of a tertiary hospital in Sierra Leone: a cross-sectional study.

Autor: Lakoh S; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone. lakoh2009@gmail.com.; Government of Sierra Leone, Ministry of Health and Sanitation, Freetown, Sierra Leone. lakoh2009@gmail.com.; Sustainable Health Systems Sierra Leone, Freetown, Sierra Leone. lakoh2009@gmail.com., Vamboi PL; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone., Ouédraogo AR; Division of Pulmonology, Training and Research Unit in Health Sciences, University Joseph KI-ZEBRO, Ouagadougou, Burkina Faso., Adekanmbi O; Department of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.; Department of Medicine, University College Hospital, Ibadan, Nigeria., Deen GF; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.; Government of Sierra Leone, Ministry of Health and Sanitation, Freetown, Sierra Leone., Russell JBW; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.; Government of Sierra Leone, Ministry of Health and Sanitation, Freetown, Sierra Leone., Sankoh-Hughes A; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone., Kamara JB; Government of Sierra Leone, Ministry of Health and Sanitation, Freetown, Sierra Leone., Kanu JE; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone., Yendewa GA; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Division of Infectious Diseases and HIV Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Firima E; Clinical Research Unit, Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.; SolidarMed, Maseru, Lesotho.; Centre for Multidisciplinary Research and Innovation, Abuja, Nigeria., Amaral AFS; National Heart and Lung Institute, Imperial College London, London, UK.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2023 Nov 16; Vol. 16 (1), pp. 337. Date of Electronic Publication: 2023 Nov 16.
DOI: 10.1186/s13104-023-06476-y
Abstrakt: Objective: Tuberculosis (TB) is a leading cause of death globally, with approximately 1.5 million deaths in 2020. TB often coexists with chronic communicable and non-communicable diseases, but data to determine the extent of comorbid diseases are limited. In this study, we aimed to assess the prevalence of TB multimorbidity and its risk factors in a tertiary hospital in Sierra Leone. This is a cross-sectional study of 240 adults with microbiologically-confirmed TB at Connaught Hospital in Freetown, between March and May 2022. Logistic regression analysis was used to identify factors associated with TB multimorbidity.
Results: The mean age of the patients was 37 years. More than two-thirds were males and about the same number had two or more chronic diseases. The most common were hypertension (47.9%) and diabetes (24.2%). Patients under 35 years of age were less likely to have TB multimorbidity (< 25 years: adjusted OR 0.07, 95%CI 0.01-0.6; 25-34 years: adjusted OR 0.2, 95%CI 0.01-0.9). We report a high prevalence of comorbid diseases among TB patients in the largest treatment center in Sierra Leone, with hypertension and diabetes being the most common. These findings support the current call for addressing comorbid non-communicable diseases in TB patients through integrated care.
(© 2023. The Author(s).)
Databáze: MEDLINE
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