Comparison of maternal and neonatal survival exposed to humidifier disinfectants during perinatal periods: a case-series study.
Autor: | Lee JH; Department of Paediatrics, Ajou University School of Medicine, 164 World Cup-ro, Yeongtong-gu, Suwon, 16499, Republic of Korea., Joh JS; Department of Pulmonology, National Medical Center, Seoul, Republic of Korea., Choi S; Department of Paediatrics, Ajou University School of Medicine, 164 World Cup-ro, Yeongtong-gu, Suwon, 16499, Republic of Korea. gabriella77@naver.com. |
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Jazyk: | angličtina |
Zdroj: | Scientific reports [Sci Rep] 2023 Nov 16; Vol. 13 (1), pp. 20026. Date of Electronic Publication: 2023 Nov 16. |
DOI: | 10.1038/s41598-023-47438-5 |
Abstrakt: | A humidifier disinfectant (HD) has been prohibited by the government due to its serious effects on the human body. Several studies on the relationship between HD and lung diseases have been performed independently on children and adults. However, there have been no reports on the effects of HD exposure on pregnant women and their foetuses. Therefore, the present study was conducted to investigate the effects of HD exposure on the foetuses of women who encountered HD during pregnancy. A total of 56 cases were recruited from 2017 to 2019 through the Korea Environmental Industry & Technology Institute, and data obtained from the medical records included maternal date of birth, maternal date of death, maternal start and end date of HD exposure, maternal date of symptom onset, neonatal birthday, neonatal birthweight, gestational age, and neonatal survival status within 28 days. All data were retrospectively investigated through medical records. Of the 47 mothers, 20 (42.6%) mothers survived, and 27 (57.4%) mothers died. In the group of survivors, there was a shorter period of total HD use, period of HD use before pregnancy and period of HD use to onset of symptoms. Shorter durations of HD use resulted in higher survival rate of mothers. HD use caused an increase in gestational age surviving foetuses, and foetal mortality increased when clinical symptoms developed before birth. (© 2023. The Author(s).) |
Databáze: | MEDLINE |
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