Cow's Milk-related Symptom Score (CoMiSS) values in presumed healthy European infants aged 6-12 months: a cross-sectional study.

Autor: Jankiewicz M; Department of Paediatrics, The Medical University of Warsaw, Żwirki I Wigury 63A, 02-091, Warsaw, Poland., Ahmed F; Department of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna, Varna, Bulgaria.; Research Group NutriLect, Department of Neuroscience, Research Institute, Medical University 'Prof. Dr. Paraskev Stoyanov', Varna, Bulgaria., Bajerova K; Department of Pediatrics, University Hospital Brno and Masaryk's University, Brno, Czech Republic.; Department of Internal Medicine, Geriatrics and Practical Medicine, University Hospital Brno and Masaryk´S University, Brno, Czech Republic., Carvajal Roca ME; Hospital La Salud, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain., Dupont C; Ramsay Group, France Et Clinique Marcel Sembat, Paris Descartes University, Boulogne-Billancourt, Paris, France., Huysentruyt K; Vrije Universiteit Brussel (VUB), UZ Brussels, KidZ Health Castle, Laarbeeklaan 101, Brussels, Belgium., Kuitunen M; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Meyer R; Department Paediatrics, Imperial College London, London, SW7 2BX, UK.; Department Dietetics, Winchester University, Winchester, SO23 4NR, UK.; Department Medicine, KU Leuven, Louvain, Belgium., Pancheva R; Department of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna, Varna, Bulgaria.; Research Group NutriLect, Department of Neuroscience, Research Institute, Medical University 'Prof. Dr. Paraskev Stoyanov', Varna, Bulgaria., Koninckx CR; Pediatric Gastroenterology, La Fe University Hospital, Instituto de Investigation Sanitaria La FE Valencia, Valencia, Spain., Salvatore S; Department of Paediatrics, University of Insubria, Varese, Italy., Shamir R; Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center, Lea and Arieh Pickel for Pediatric Research, Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Staiano A; Department of Translational Medical Science, Section of Pediatrics, University Federico II, Naples, Italy., Vandenplas Y; Vrije Universiteit Brussel (VUB), UZ Brussels, KidZ Health Castle, Laarbeeklaan 101, Brussels, Belgium., Szajewska H; Department of Paediatrics, The Medical University of Warsaw, Żwirki I Wigury 63A, 02-091, Warsaw, Poland. szajewska@gmail.com.
Jazyk: angličtina
Zdroj: European journal of pediatrics [Eur J Pediatr] 2024 Feb; Vol. 183 (2), pp. 707-713. Date of Electronic Publication: 2023 Nov 17.
DOI: 10.1007/s00431-023-05334-0
Abstrakt: The Cow's Milk-related Symptom Score (CoMiSS) is an awareness tool for evaluating cow's milk-related symptoms. Previous studies have focused on providing CoMiSS values for healthy and symptomatic infants aged 0-6 months. However, there is a notable gap in the literature concerning CoMiSS values for infants older than 6 months. This cross-sectional study aimed to determine CoMiSS values in presumed healthy infants who have completed 6 months and are up to 12 months old, hereafter referred to as 6 to 12 months old. Physicians from six European countries prospectively determined CoMiSS values in infants attending well-child clinics. Exclusion criteria included preterm delivery, acute or chronic disease, and the consumption of a therapeutic formula, dietary supplements (except vitamins), or medication. The following information was collected: gestational age, gender, age, type of feed (breast milk or infant formula), and complementary feeding. Descriptive statistics were summarized with mean and standard deviation for normally distributed continuous variables, median and IQR for non-normally distributed variables, and differences in CoMiSS values were analyzed with appropriate tests. Data from 609 infants were obtained. The overall median (Q1-Q3) CoMiSS values were 3 (1-5). Significant differences were found across age groups (p < 0.001), but not across groups based on gender (p = 0.551) or feeding type (p = 0.880).   Conclusions: This study provided CoMiSS values in presumed healthy infants aged 6-12 months. Additional studies should be conducted to establish the use of CoMiSS to assess cow's milk-related symptoms in infants 6 months and older. What is Known: • The Cow's Milk-related Symptom Score (CoMiSS) is an awareness tool for evaluating symptoms related to cow's milk. • CoMiSS values for presumed healthy infants aged 0-6 months infants are already available. What is New: • CoMiSS values in European infants aged 6-12 months are provided. • These CoMiSS values differed across various age groups but not across groups based on gender or feeding type.
(© 2023. The Author(s).)
Databáze: MEDLINE
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