[Frequency of tuberculosis and the impact of immunosuppression in people living with HIV (PLHIV) followed at the Regional Hospital Center of Maradi, Niger].

Autor: Abdoulaye O; Laboratoire de biologie Médicale, Centre Hospitalier Régional de Maradi, Faculté de Sciences de la Santé, Université Dan Dicko DanKoulodo de Maradi, Niger., Harouna Amadou ML; Service de Maladies infectieuses, Centre Hospitalier Régional de Maradi, Faculté de Sciences de la Santé, Université Dan Dicko DanKoulodo de Maradi, Niger., Biraima A; Service de Médecine Interne, Centre Hospitalier Régional de Maradi, Université Dan Dicko Dankoulodo de Maradi, Niger., Amadou O; Service de Maladies infectieuses, Centre Hospitalier Régional de Maradi, Faculté de Sciences de la Santé, Université Dan Dicko DanKoulodo de Maradi, Niger., Doutchi M; Service de Maladies infectieuses et Tropicales, Hôpital National de Zinder, Faculté des Sciences de la Santé, Université de Zinder, Niger., Maiga DA; Laboratoire de biologie Médiale, Hôpital National de Niamey, Université Abdou Moumouni de Niamey, Niger., Tawaye I; Service de Médecine Interne, Centre Hospitalier Régional de Maradi., Issa M; Laboratoire de Biologie, Centre Hospitalier Régional de Maradi, Niger.
Jazyk: francouzština
Zdroj: Le Mali medical [Mali Med] 2021; Vol. 36 (3), pp. 20-23.
Abstrakt: Objective: Objective of this study was to determine the frequency of tuberculosis (TB) and the impact of immunosuppression in patients living with HIV (PvVIH) monitored at the Regional Hospital Center (CHR) of Maradi.
Methods: That was a retrospective study based on the medical records of PvVIH followed in the infectious diseases department of the CHR of Maradi. All HIV-positive adults were included in regular consultations between January 2013 and September 2018.
Results: A total of 872 patients were included. The average age of the cohort was 36.10 years ± 11,53. Of these patients, 15 had tuberculosis infection with a frequency of 1.72% (95% CI: 1.05 - 2.82) and 429 a CD4 T cell count of less than 200 / mm3. Of the 15 co-infected HIV / TB patients, 60% had a CD4 T cell count of less than 200 / mm3 (p = 0.78). HIV1 was tested in 98.73% of cases, HIV2 in 0.69% and both types of virus in 0.58% of cases. All patients who had a TB infection were HIV1 +.
Conclusion: Knowledge about the prevalence and impact of TB in people living with HIV is needed to establish a mechanism for controlling this disease. It is more than necessary to prevent TB among PLWHIV when CD4 counts begin to decline.
(Le comité de rédaction se réserve le droit de renvoyer aux auteurs avant toute soumission à l'avis des lecteurs les manuscrits qui ne seraient pas conformes à ces modalités de présentation. En outre il leur conseille de conserver un exemplaire du manuscrit, des figures et des tableaux.)
Databáze: MEDLINE
Externí odkaz: