Emergency Liver Retransplantation With Marginal Donors.

Autor: Cuevas López MJ; Virgen del Rocio University Hospital, Seville, Spain. Electronic address: marijose.cuevas@gmail.com., Bellido CB; Virgen del Rocio University Hospital, Seville, Spain., Franco CC; Virgen del Rocio University Hospital, Seville, Spain., Artacho GS; Virgen del Rocio University Hospital, Seville, Spain., Gómez LMM; Virgen del Rocio University Hospital, Seville, Spain., Martínez JMÁ; Virgen del Rocio University Hospital, Seville, Spain., Ruiz FJP; Virgen del Rocio University Hospital, Seville, Spain., Bravo MÁG; Virgen del Rocio University Hospital, Seville, Spain.
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2023 Dec; Vol. 55 (10), pp. 2282-2284. Date of Electronic Publication: 2023 Nov 14.
DOI: 10.1016/j.transproceed.2023.09.012
Abstrakt: Background: The goal of the present study is to determine if using marginal donors negatively impacts the outcomes of emergency liver retransplantation.
Methods: A retrospective case-control study was performed, including all emergency liver retransplantations done in our center between 1990 and 2021. Recipients from the control group received the second grafts from "ideal donors", and patients from the case group received them from marginal donors. Analyzed variables included demographics of recipients and donors, complications, and survival rates.
Results: 38 emergency retransplantations were performed. 23 recipients were included in the control group, and the remaining 15 were in the case group. The second donors from the case group were significantly older (mean age 58 vs 71 years old, P < 0.0001). On the contrary, there were no differences between groups regarding the mean age of recipients, comorbidities, Model for End-Stage Liver Disease scores, or causes of retransplantation (the most common was hepatic artery thrombosis). No differences were found in early perioperative death rates (control group 26.1% vs case group 20%, P =1) and, although the case group seemed to have slightly poorer outcomes in long-term survival (control group 70%, 61%, and 55% vs case group 73%, 59%, and 39%, respectively, at 1, 5, and 10 years), the differences were not statistically significant (log-rank = 0.808).
Conclusions: The use of marginal donors for emergency liver retransplantation was proved safe in our study, as there were no differences in complications or in short- or mid-term survival rates.
Competing Interests: Declaration of Competing Interest All the authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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