Nosocomial fungemia in neonates associated with intravascular pressure-monitoring devices.

Autor: Solomon SL, Alexander H, Eley JW, Anderson RL, Goodpasture HC, Smart S, Furman RM, Martone WJ
Jazyk: angličtina
Zdroj: Pediatric infectious disease [Pediatr Infect Dis] 1986 Nov-Dec; Vol. 5 (6), pp. 680-5.
DOI: 10.1097/00006454-198611000-00016
Abstrakt: In the period from January, 1982, to March, 1983, eight infants in the neonatal intensive care unit at one hospital had blood cultures positive for Candida parapsilosis; six cases had occurred after December, 1982. Epidemiologic investigation included a case-control study comparing the 8 cases with 29 birth weight-matched controls. Logistic regression analysis indicated that the model that best fit the observed data included the following risk factors for fungemia: duration of umbilical artery catheterization; duration of receipt of parenteral nutrition; and estimated gestational age. Parenteral nutrition therapy was often administered through the umbilical artery catheters, which were also used for monitoring arterial pressure; transducer domes thus contained parenteral nutrition fluid. Transducers were usually disinfected with alcohol. Laboratory investigation showed that the heads of 6 of 11 in-use blood pressure transducers and 1 of 4 transducers in storage after cleaning were culture-positive for C. parapsilosis. After control measures were instituted no further cases occurred.
Databáze: MEDLINE