Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effects.

Autor: Méndez Rodríguez KB; Coordinación para la Innovación y Aplicación de la Ciencia y Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí (UASLP), San Luis Potosí, San Luis Potosí, México., Jiménez Avalos JA; Centro de Investigación y Desarrollo Oncológico, S.A. de C.V. (CIDO), San Luis Potosí, San Luis Potosí, México., Fernández Macias JC; Coordinación para la Innovación y Aplicación de la Ciencia y Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí (UASLP), San Luis Potosí, San Luis Potosí, México., González Palomo AK; Coordinación para la Innovación y Aplicación de la Ciencia y Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí (UASLP), San Luis Potosí, San Luis Potosí, México. karen.palomo@uaslp.mx.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2023 Dec; Vol. 30 (57), pp. 119733-119749. Date of Electronic Publication: 2023 Nov 16.
DOI: 10.1007/s11356-023-30853-6
Abstrakt: Microplastics (MPs) have attracted global interest because they have been recognized as emerging pollutants that require urgent attention. MPs are plastic particles with a size between 1 micron and 5 mm (1 µm-5mm); those measuring less than 1 µm are known as nanoplastics (NPs). MP is distributed in the environment in various physical forms that depend on the degradation process, the erosion factors to which it was subjected, or the original form in which it was intentionally manufactured. Humans may be exposed to these pollutants mainly by ingestion or inhalation, which could adversely affect human health with effects that are still unknown due to limitations that are often dependent on their analytical determination and lack of studies over time, as it is a relatively new topic. Therefore, this review focuses on the challenges currently faced by laboratories for determining MPs in different matrices. We highlight the application of methods and techniques to assess the precise levels of exposure to MPs in biological samples. In addition, exposure pathways, sources, and evidence of adverse effects reported in vitro and in vivo studies are described to generate knowledge about their potential threat to human health.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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