| Autor: |
Fluitman KS; Department of Internal Medicine, Amsterdam University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, 1081 HV Amsterdam, The Netherlands., van den Broek T; Department of Microbiology and Systems Biology, TNO Earth, Life and Social Sciences, 3704 HE Zeist, The Netherlands., Reinders I; Amsterdam Public Health Research Institute, 1081 HV Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Wijnhoven HAH; Amsterdam Public Health Research Institute, 1081 HV Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., Nieuwdorp M; Department of Internal Medicine, Amsterdam University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands.; Department of Vascular Medicine, Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands., Visser M; Amsterdam Public Health Research Institute, 1081 HV Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands., IJzerman RG; Department of Internal Medicine, Amsterdam University Medical Centers, Location VUmc, 1081 HV Amsterdam, The Netherlands., Keijser BJF; Department of Microbiology and Systems Biology, TNO Earth, Life and Social Sciences, 3704 HE Zeist, The Netherlands.; Department of Preventive Dentistry, Academic Center for Dentistry Amsterdam, University of Amsterdam and VU University, 1081 LA Amsterdam, The Netherlands. |
| Abstrakt: |
Nutrition and oral health are closely related, especially in older adults in whom poor nutrition may lead to oral microbial perturbations, exacerbating poor oral health. In a 6-month randomized controlled trial, we evaluated the effects on oral microbiota and on oral health of dietary advice aimed at increasing protein intake to ≥1.2 g/kg adjusted body weight/day (g/kg aBW/d) in community-dwelling older adults with low habitual protein intake (<1.0 g/kg aBW/d). Food intake was measured via 24 h dietary recalls, oral health was measured via questionnaires, and oral microbial composition was assessed via the 16S rRNA sequencing of tongue swabs. Mean baseline protein intake was 0.8 g/kg aBW/day in both groups. In the high protein group ( n = 47), participants increased their protein intake to mean 1.2 g/kg aBW/day at the 6-month follow-up. Protein intake in the control group ( n = 43) remained at 0.9 g/kg a BW/day. The intervention did not affect self-reported oral health. While it caused moderate shifts in oral microbiota alpha- and beta-diversity measures, abundances of individual bacterial taxa were not affected. In conclusion, our intervention did not affect self-reported oral health within a period of 6 months, nor did it substantially affect the tongue microbiota composition. |
