Systematic review and meta-analysis of sedentary behavior in persons with multiple sclerosis.

Autor: Zheng P; Department of Kinesiology and Nutrition, University of Illinois Chicago, 545 AHSB, 1919 W. Taylor St., Chicago, IL 60612, United States. Electronic address: pxzheng@uic.edu., DeJonge SR; Department of Kinesiology and Nutrition, University of Illinois Chicago, 545 AHSB, 1919 W. Taylor St., Chicago, IL 60612, United States., Flores VA; Department of Kinesiology and Nutrition, University of Illinois Chicago, 545 AHSB, 1919 W. Taylor St., Chicago, IL 60612, United States., Jeng B; Department of Kinesiology and Nutrition, University of Illinois Chicago, 545 AHSB, 1919 W. Taylor St., Chicago, IL 60612, United States., Motl RW; Department of Kinesiology and Nutrition, University of Illinois Chicago, 545 AHSB, 1919 W. Taylor St., Chicago, IL 60612, United States.
Jazyk: angličtina
Zdroj: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2023 Dec; Vol. 80, pp. 105124. Date of Electronic Publication: 2023 Nov 09.
DOI: 10.1016/j.msard.2023.105124
Abstrakt: Background: Persons with multiple sclerosis (MS) engage in less physical activity than the general population, and the disease manifestations and comorbidity conditions might further predispose them toward sedentary behavior (SB) among this population. We performed a systematic review with meta-analysis of studies that compared SB in persons with MS and non-MS controls, and examined factors that may moderate the difference in SB between the two groups.
Methods: We conducted a systematic search using PubMed, PsycINFO, Scopus, and CINAHL from inception up to August 2022, and identified studies that involved group comparison of SB outcomes between MS and non-MS controls. Effect sizes were calculated as standardized mean differences (SMDs) using Hedge's g. We generated a multilevel random-effects model for estimating an overall effect, and performed moderator analyses. Methodological quality was assessed using the Appraisal Tool for Cross-Sectional Studies (AXIS tool).
Results: Eleven studies were included (1403 MS vs. 449 controls) and yielded 17 effects for meta-analysis. Results indicated an overall small, but significant effect (SMD [95% CI] = 0.27 [0.02, 0.53], p = 0.03) with significant heterogeneity (Q 16  = 72.2, p < 0.01; I 2 total  = 75.8%). There were larger effects when the MS sample had a higher proportion of females, or when SB was reported as percent sedentary time per day compared with other SB outcomes (p = 0.03 and 0.05, respectively). The included studies achieved fairly good quality (91.4%) using the AXIS tool.
Conclusions: The cumulative evidence supports that persons with MS engage in more SB than non-MS controls. Our findings may support the design of targeted behavioral change interventions for reducing SB and improving health and function in the MS population.
Competing Interests: Declaration of Competing Interest None declare.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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