Study on damage of the macrostructure of the cochlea under the impact load.

Autor:	Wang J; School of Mechanics and Engineering Science, Shanghai University, Shanghai, China.; Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai, China., Liang J; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Gao L; School of Mechanics and Engineering Science, Shanghai University, Shanghai, China.; Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai, China., Yao W; School of Mechanics and Engineering Science, Shanghai University, Shanghai, China.; Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai, China.
Jazyk:	angličtina
Zdroj:	Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine [Proc Inst Mech Eng H] 2023 Dec; Vol. 237 (12), pp. 1390-1399. Date of Electronic Publication: 2023 Nov 13.
DOI:	10.1177/09544119231209187
Abstrakt:	Due to the tiny and delicate structure of the cochlea, the auditory system is the most sensitive to explosion impact damage. After being damaged by the explosion impact wave, it usually causes long-term deafness, tinnitus, and other symptoms. To better understand the influence of impact load on the cochlea and basilar membrane (BM), a three-dimensional (3D) fluid-solid coupling finite element model was developed. This model accurately reflects the actual spatial spiral shape of the human cochlea, as well as the lymph environment and biological materials. Based on verifying the reliability of the model, the curve of impact load-amplitude response was obtained, and damage of impact load on the cochlea and the key macrostructure-BM was analyzed. The results indicate that impact wave at middle frequency has widest influence on the cochlea. Furthermore, impact loading causes tears in the BM and destroys the cochlear frequency selectivity. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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