VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023.

Autor:	Alvarez-Jarreta J; European Bioinformatics Institute, Hinxton CB10 1SD, UK., Amos B; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Aurrecoechea C; University of Georgia, Athens, GA 30602, USA., Bah S; School of Infection and Immunity, University of Glasgow, Glasgow, UK., Barba M; European Bioinformatics Institute, Hinxton CB10 1SD, UK., Barreto A; University of Pennsylvania, Philadelphia, PA 19104, USA., Basenko EY; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Belnap R; University of Georgia, Athens, GA 30602, USA., Blevins A; University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Böhme U; University of Georgia, Athens, GA 30602, USA., Brestelli J; University of Pennsylvania, Philadelphia, PA 19104, USA., Brown S; University of Pennsylvania, Philadelphia, PA 19104, USA., Callan D; University of Pennsylvania, Philadelphia, PA 19104, USA., Campbell LI; European Bioinformatics Institute, Hinxton CB10 1SD, UK., Christophides GK; Imperial College London, South Kensington, London SW7 2BU, UK., Crouch K; School of Infection and Immunity, University of Glasgow, Glasgow, UK., Davison HR; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., DeBarry JD; University of Georgia, Athens, GA 30602, USA., Demko R; University of Pennsylvania, Philadelphia, PA 19104, USA., Doherty R; University of Pennsylvania, Philadelphia, PA 19104, USA., Duan Y; University of Pennsylvania, Philadelphia, PA 19104, USA., Dundore W; University of Georgia, Athens, GA 30602, USA., Dyer S; European Bioinformatics Institute, Hinxton CB10 1SD, UK., Falke D; University of Georgia, Athens, GA 30602, USA., Fischer S; University of Pennsylvania, Philadelphia, PA 19104, USA., Gajria B; University of Pennsylvania, Philadelphia, PA 19104, USA., Galdi D; University of Pennsylvania, Philadelphia, PA 19104, USA., Giraldo-Calderón GI; University of Notre Dame, Notre Dame, IN 46556, USA., Harb OS; University of Pennsylvania, Philadelphia, PA 19104, USA., Harper E; University of Pennsylvania, Philadelphia, PA 19104, USA., Helb D; University of Pennsylvania, Philadelphia, PA 19104, USA., Howington C; University of Notre Dame, Notre Dame, IN 46556, USA., Hu S; University of Pennsylvania, Philadelphia, PA 19104, USA., Humphrey J; University of Georgia, Athens, GA 30602, USA., Iodice J; University of Pennsylvania, Philadelphia, PA 19104, USA., Jones A; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Judkins J; University of Pennsylvania, Philadelphia, PA 19104, USA., Kelly SA; Imperial College London, South Kensington, London SW7 2BU, UK., Kissinger JC; University of Georgia, Athens, GA 30602, USA., Kittur N; University of Georgia, Athens, GA 30602, USA., Kwon DK; University of Notre Dame, Notre Dame, IN 46556, USA., Lamoureux K; University of Georgia, Athens, GA 30602, USA., Li W; University of Pennsylvania, Philadelphia, PA 19104, USA., Lodha D; European Bioinformatics Institute, Hinxton CB10 1SD, UK., MacCallum RM; Imperial College London, South Kensington, London SW7 2BU, UK., Maslen G; Imperial College London, South Kensington, London SW7 2BU, UK., McDowell MA; University of Notre Dame, Notre Dame, IN 46556, USA., Myers J; University of Pennsylvania, Philadelphia, PA 19104, USA., Nural MV; University of Georgia, Athens, GA 30602, USA., Roos DS; University of Pennsylvania, Philadelphia, PA 19104, USA., Rund SSC; University of Notre Dame, Notre Dame, IN 46556, USA., Shanmugasundram A; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.; Genomics England Limited, London E14 5AB, UK., Sitnik V; European Bioinformatics Institute, Hinxton CB10 1SD, UK., Spruill D; University of Georgia, Athens, GA 30602, USA., Starns D; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Tomko SS; University of Pennsylvania, Philadelphia, PA 19104, USA., Wang H; University of Georgia, Athens, GA 30602, USA., Warrenfeltz S; University of Georgia, Athens, GA 30602, USA., Wieck R; University of Notre Dame, Notre Dame, IN 46556, USA., Wilkinson PA; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Zheng J; University of Pennsylvania, Philadelphia, PA 19104, USA.
Jazyk:	angličtina
Zdroj:	Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D808-D816.
DOI:	10.1093/nar/gkad1003
Abstrakt:	The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) is a Bioinformatics Resource Center funded by the National Institutes of Health with additional funding from the Wellcome Trust. VEuPathDB supports >600 organisms that comprise invertebrate vectors, eukaryotic pathogens (protists and fungi) and relevant free-living or non-pathogenic species or hosts. Since 2004, VEuPathDB has analyzed omics data from the public domain using contemporary bioinformatic workflows, including orthology predictions via OrthoMCL, and integrated the analysis results with analysis tools, visualizations, and advanced search capabilities. The unique data mining platform coupled with >3000 pre-analyzed data sets facilitates the exploration of pertinent omics data in support of hypothesis driven research. Comparisons are easily made across data sets, data types and organisms. A Galaxy workspace offers the opportunity for the analysis of private large-scale datasets and for porting to VEuPathDB for comparisons with integrated data. The MapVEu tool provides a platform for exploration of spatially resolved data such as vector surveillance and insecticide resistance monitoring. To address the growing body of omics data and advances in laboratory techniques, VEuPathDB has added several new data types, searches and features, improved the Galaxy workspace environment, redesigned the MapVEu interface and updated the infrastructure to accommodate these changes. (© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.)
Databáze:	MEDLINE
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