| Autor: |
Yokota K; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan., Morimoto K; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan., Yazawa H; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan., Tsuzuki Wada T; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan., Sakamoto T; Department of Hematology, Faculty of Medicine, Saitama Medical University, Japan., Terui Y; Department of Hematology, Faculty of Medicine, Saitama Medical University, Japan., Kaneko S; Department of Nephrology, Faculty of Medicine, Saitama Medical University, Japan., Inoue T; Department of Nephrology, Faculty of Medicine, Saitama Medical University, Japan., Okada H; Department of Nephrology, Faculty of Medicine, Saitama Medical University, Japan., Akiyama Y; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan., Mimura T; Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan. |
| Abstrakt: |
We herein report a case of diffuse large B-cell lymphoma (DLBCL) involving multiple renal and bone infiltrations presenting with giant cell arteritis (GCA)-like manifestations. One month prior, the present patient had left-sided temporal headache, jaw claudication, and renal failure. The patient was diagnosed with DLBCL based on a renal biopsy. After rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone plus intrathecal methotrexate/cytarabine/prednisone and rituximab, high-dose methotrexate, and cytarabine chemotherapy, the patient's clinical manifestations improved, and complete remission was achieved. DLBCL rarely but occasionally presents with GCA-like manifestations or multiple renal and bone infiltrations, highlighting the need for prompt and aggressive combination chemotherapy. |
