Fungicides from rice cultivation (tebuconazole and azoxystrobin) alters biochemical and histological markers of hammertoad tadpoles (Boanafaber).

Autor: Warsneski A; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Bitschinski D; Biodiversity Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Rutkoski CF; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Israel NG; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Pereira Gonçalves GH; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Lã L; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Guerreiro F; Biodiversity Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Menta Giasson LO; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Coelho de Albuquerque CA; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Hasckel RP; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Barbosa da Silva E; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil., Alves TC; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil., Alves de Almeida E; Environmental Engineering Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil; Biodiversity Post-Graduation Program, University of Blumenau, Blumenau, SC, Brazil; Department of Natural Science, University of Blumenau, Blumenau, SC, Brazil. Electronic address: eduardoalves@furb.br.
Jazyk: angličtina
Zdroj: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2024 Jan 15; Vol. 341, pp. 122900. Date of Electronic Publication: 2023 Nov 10.
DOI: 10.1016/j.envpol.2023.122900
Abstrakt: Tebuconazole (TBZ) and azoxystrobin (AZX) are fungicides frequently used in rice cultivation. Despite protecting crops against fungal diseases, these compounds can contaminate the natural environments close to the crops, exerting negative effects on non-target organisms, the present study aimed to characterize the contamination by fungicides of a river that flows in an area dominated by rice cultivation in the north of the state of Santa Catarina, SC, Brazil. Concentrations of TBZ and AZX found in the field were used to evaluate their negative effects on development, biochemical biomarkers and histopatology of the liver of a native tadpole species, the hammerfrog (Boana faber). Tadpoles were exposed for 16 days to the lowest (1.20 μg/L) and highest (2.60 μg/L) concentration of TBZ, lowest (0.70 μg/L) and highest (1.60 μg/L) concentration of AZX, and the mix of both fungicides at lowest and highest concentration of each found in field analyses. Exposure to the lower TBZ concentration and both concentrations of the Mix accelerated the development of tadpoles. AZX caused an increase in the activities of glutathione S-transferase (GST), carboxylesterase (CbE) and glucose-6-phosphate dehydrogenase (G6PDH) in the liver, an increase in the levels of protein carbonyls (PC) in the liver and an increase in the activity of acetylcholinesterase (AChE) in muscle of tadpoles. TBZ, on the other hand, generated an increase in GST, G6PDH, PC and histopathological severity scores in liver and in muscle AChE activity. The effects were more intense in the groups exposed to the Mix of contaminants. No treatment altered brain AChE. The data showed that the fungicides from in rice cultivation found in natural aquatic environments around the crops pose risks to the health of the animals, compromising their metabolism and development.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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