The minus strand of positive-sense RNA viruses encodes small proteins.

Autor: Cheng X; College of Plant Protection/Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region of Chinese Education Ministry, Northeast Agricultural University, 150030 Harbin, Heilongjiang, China. Electronic address: xfcheng@neau.edu.cn., Wu X; College of Plant Protection/Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region of Chinese Education Ministry, Northeast Agricultural University, 150030 Harbin, Heilongjiang, China., Fang R; State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: fangrx@im.ac.cn.
Jazyk: angličtina
Zdroj: Trends in microbiology [Trends Microbiol] 2024 Jan; Vol. 32 (1), pp. 6-7. Date of Electronic Publication: 2023 Nov 10.
DOI: 10.1016/j.tim.2023.10.012
Abstrakt: It is widely accepted that the minus strands of positive single-strand RNA (+ssRNA) viruses function as replication templates only. Gong et al. revealed that the minus strand of two unrelated +ssRNA viruses encodes proteins. This textbook-changing discovery calls for the reconsideration of the molecular mechanisms underlying the infection cycle of +ssRNA viruses.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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