Associations between occupational physical activity and left ventricular structure and function over 25 years in CARDIA.

Autor:	Quinn TD; Department of Epidemiology and Biostatistics, West Virginia University School of Public Health, 1 Medical Drive, Morgantown, WV 26506, USA., Lane A; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, 921 Assembly Street, Columbia, SC 29201, USA.; Department of Applied Exercise Science, School of Kinesiology, University of Michigan, 830 N University Ave, Ann Arbor, MI 48130, USA., Pettee Gabriel K; Department of Epidemiology, The University of Alabama at Birmingham, 170 2nd Ave. South, RPHB 230J, Birmingham, AL 35294, USA., Sternfeld B; Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94611, USA., Jacobs DR Jr; Mayo Professor of Public Health, Division of Epidemiology and Community Health, University of Minnesota, 1300 2nd Streetm Suite 300, Minneapolis, MN 55454, USA., Smith P; Institute for Work and Health, 400 University Avenue, Suite 1800, Toronto, ON, M5G 1S5, Canada.; Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, ON, M5T 3M7, Canada.; Department of Epidemiology and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC 3004, Australia., Barone Gibbs B; Department of Epidemiology and Biostatistics, West Virginia University School of Public Health, 1 Medical Drive, Morgantown, WV 26506, USA.
Jazyk:	angličtina
Zdroj:	European journal of preventive cardiology [Eur J Prev Cardiol] 2024 Mar 04; Vol. 31 (4), pp. 425-433.
DOI:	10.1093/eurjpc/zwad349
Abstrakt:	Aims: Leisure time physical activity (LTPA) confers cardiovascular health benefits, while occupational physical activity (OPA) may have paradoxically negative health associations. This study tested the explanatory hypothesis that unfavourable cardiac remodelling may result from chronic OPA-induced cardiovascular strain. Methods and Results: Longitudinal associations of OPA and left ventricular (LV) structure and function were examined in 1462 participants {50.0% female, 56.4% White, aged 30.4 ± 3.4 years at baseline [Year 5 exam (1990-91)]} from the Coronary Artery Risk Development in Young Adults study. Left ventricular structure and function were measured as LV mass (LVMi), end-diastolic volume (LVEDVi), end-systolic volume (LVESVi), ejection fraction (LVEF), stroke volume (LVSVi), and e/a-wave ratio (EA ratio) via echocardiography at baseline and 25 years later. Occupational physical activity was reported at seven exams during the study period as months/year with 'vigorous job activities such as lifting, carrying, or digging' for ≥5 h/week. The 25-year OPA patterns were categorized into three trajectories: no OPA (n = 770), medium OPA (n = 410), and high OPA (n = 282). Linear regression estimated associations between OPA trajectories and echocardiogram variables at follow-up after adjusting for baseline values, individual demographic/health characteristics, and LTPA. Twenty-five-year OPA exposure was not significantly associated with LVMi, LVEDVi, LVSVi, or EA ratio (P > 0.05). However, higher LVESVi (β = 1.84, P < 0.05) and lower LVEF (β = -1.94, P < 0.05) were observed at follow-up among those in the high- vs. no-OPA trajectories. Conclusion: The paradoxically adverse association of OPA with cardiovascular health was partially supported by null or adverse associations between high OPA and echocardiogram outcomes. Confirmation is needed using more precise OPA measures. Competing Interests: Conflict of interest: none declared. (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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