Understanding How Minerals Contribute to Optimal Immune Function.

Autor: Stefanache A; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania., Lungu II; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania., Butnariu IA; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania., Calin G; Faculty of Dental Medicine, 'Apollonia' University of Iasi, 11 Pacurari Street, Iasi 700511, Romania., Gutu C; Faculty of Medicine and Pharmacy, University Dunarea de Jos, 47 Domneasca Street, Galati 800008, Romania., Marcu C; Faculty of Medicine and Pharmacy, University Dunarea de Jos, 47 Domneasca Street, Galati 800008, Romania., Grierosu C; Faculty of Dental Medicine, 'Apollonia' University of Iasi, 11 Pacurari Street, Iasi 700511, Romania., Bogdan Goroftei ER; Faculty of Medicine and Pharmacy, University Dunarea de Jos, 47 Domneasca Street, Galati 800008, Romania., Duceac LD; Faculty of Medicine and Pharmacy, University Dunarea de Jos, 47 Domneasca Street, Galati 800008, Romania., Dabija MG; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania., Popa F; Faculty of Medicine and Pharmacy, University Dunarea de Jos, 47 Domneasca Street, Galati 800008, Romania., Damir D; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania.
Jazyk: angličtina
Zdroj: Journal of immunology research [J Immunol Res] 2023 Nov 01; Vol. 2023, pp. 3355733. Date of Electronic Publication: 2023 Nov 01 (Print Publication: 2023).
DOI: 10.1155/2023/3355733
Abstrakt: Sufficient mineral supply is vital not only for the innate immune system but also for the components of the adaptive immune defense, which encompass defense mechanisms against pathogens and the delicate balance of pro- and anti-inflammatory regulation in the long term. Generally, a well-balanced diet is capable of providing the necessary minerals to support the immune system. Nevertheless, specific vulnerable populations should be cautious about obtaining adequate amounts of minerals such as magnesium, zinc, copper, iron, and selenium. Inadequate levels of these minerals can temporarily impair immune competence and disrupt the long-term regulation of systemic inflammation. Therefore, comprehending the mechanisms and sources of these minerals is crucial. In exceptional circumstances, mineral deficiencies may necessitate supplementation; however, excessive intake of supplements can have adverse effects on the immune system and should be avoided. Consequently, any supplementation should be approved by medical professionals and administered in recommended doses. This review emphasizes the crucial significance of minerals in promoting optimal functioning of the immune system. It investigates the indispensable minerals required for immune system function and the regulation of inflammation. Moreover, it delves into the significance of maintaining an optimized intake of minerals from a nutritional standpoint.
Competing Interests: The authors declare no conflict of interest.
(Copyright © 2023 Alina Stefanache et al.)
Databáze: MEDLINE
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