Transmission Coefficient-Based Monitoring of Microwave Ablation: Development and Experimental Evaluation in Ex Vivo Tissue.
| Autor: | Zeinali N, Sebek J, Fallahi H, Pfannenstiel A, Prakash P |
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| Jazyk: | angličtina |
| Zdroj: | IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2024 Apr; Vol. 71 (4), pp. 1269-1280. Date of Electronic Publication: 2024 Mar 20. |
| DOI: | 10.1109/TBME.2023.3331659 |
| Abstrakt: | Objectives: To assess the feasibility of monitoring transient evolution of thermal ablation zones with a microwave transmission coefficient-based technique. Methods: Microwave ablation was performed in ex vivo bovine liver with two 2.45 GHz directional antennas. A custom apparatus was developed to enable periodic switching between "heating mode" when power from the generator was coupled to the antennas, and "monitoring mode", when antennas were coupled to a network analyzer for broadband transmission coefficient ( s Results: Normalized average transmission coefficient initially rapidly decreased and then increased before asymptotically approaching steady state, with the transition time ranging between 53 s (45 W) and 109 s (30 W). Analysis of ground truth ablation zone images indicated time to complete ablation of 230-350 s. The relative prediction error for time to complete ablation derived from the s Conclusion: We have demonstrated the feasibility of monitoring transient evolution of thermal ablation zones using microwave transmission coefficient measurements in ex vivo tissue. Significance: The presented technique has potential to contribute towards addressing the clinical need for a method of monitoring evolution of thermal ablation zones. |
| Databáze: | MEDLINE |
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