Superior Vesical Fissure as an Incomplete Form of Bladder Exstrophy: A Case Report with Clinico-Pathological Correlation and a Comprehensive Literature Review.

Autor: Arredondo Montero J; Pediatric Surgery Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain., Bronte Anaut M; Pathology Department, Hospital Universitario de Araba, Vitoria, Spain., Molina Caballero AY; Pediatric Surgery Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain., Carracedo Vega E; Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain., Guarch Troyas R; Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain., Pérez-Martínez A; Pediatric Surgery Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain.
Jazyk: angličtina
Zdroj: International journal of surgical pathology [Int J Surg Pathol] 2024 Aug; Vol. 32 (5), pp. 999-1008. Date of Electronic Publication: 2023 Nov 08.
DOI: 10.1177/10668969231206348
Abstrakt: Multiple variants of classic bladder exstrophy have been described, all of them infrequent. Superior vesical fissure is a mild variant of this pathology in which genital involvement is scarce or absent. To date, there are only isolated reports of this entity. We report a full-term female patient of Arabian descent with a clinical and radiological diagnosis of superior vesical fissure that was surgically corrected in our center with a favorable evolution. Histological study, supported by immunohistochemical techniques, showed squamous and transitional epithelium and discrete chronic inflammation. Our literature review identified 26 reports of superior vesical fissure (including ours), with high heterogeneity in terms of clinical characterization and associated malformations and with only two histological reports. The clinical evolution of the patients reported in the literature was favorable, with lower morbidity and mortality than in classical forms of bladder exstrophy.
Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE