Outcomes and Complications 5 Years After Surgery for Pediatric Cataract Associated With Persistent Fetal Vasculature.

Autor: Haider KM; Riley Hospital for Children (K.M.H.), Indianapolis, Indiana, USA. Electronic address: pedig@jaeb.org., Repka MX; Wilmer Eye Institute (M.X.R.), Baltimore, Maryland, USA., Sutherland DR; Jaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA., Hatt SR; Mayo Clinic (S.R.H.), Rochester, Minnesota, USA., Fallaha N; Centre Hospitalier Universitaire Sainte-Justine (N.F.), Montreal, Quebec, Canada., Kraker RT; Jaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA., Melia BM; Jaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA., Cotter SA; Southern California College of Optometry (S.A.C.), Marshall B. Ketchum University, Fullerton, California, USA., Holmes JM; University of Arizona-Tucson (J.M.H.), Tucson, Arizona, USA.
Jazyk: angličtina
Zdroj: American journal of ophthalmology [Am J Ophthalmol] 2024 Apr; Vol. 260, pp. 30-36. Date of Electronic Publication: 2023 Nov 07.
DOI: 10.1016/j.ajo.2023.11.002
Abstrakt: Purpose: To report 5-year outcomes after surgery for cataract associated with persistent fetal vasculature (PFV).
Design: Clinical cohort study using pediatric cataract registry data collected annually from medical records.
Methods: This study included 64 children <13 years of age who were undergoing surgery for unilateral, nontraumatic cataract associated with PFV. Proportions with age-normal visual acuity (VA) and VA better than 20/200 at 5 years' follow-up were estimated. Cumulative incidences of complications and additional surgeries by 5 years were calculated. Outcomes were compared between eyes with unilateral PFV and eyes with unilateral non-PFV cataract from our registry.
Results: Forty-eight of 64 eyes were aphakic postoperatively (median age at surgery 2 months [range 1-13 months]) and 16 were pseudophakic (29 months [range 2-92 months]). Overall, 4 of 42 eyes (10% [95% confidence interval {CI} 3%-23%]) achieved age-normal VA. VA better than 20/200 was achieved in 17 (59% [95% CI 39%-76%]) unilateral aphakic PFV eyes and 44 (43% [95% CI 32%-54%]) unilateral non-PFV aphakic eyes (age-adjusted odds ratio = 1.90 [95% CI 0.81-4.50]; P = .14). The most common complication in aphakic PFV eyes was glaucoma-related adverse events (cumulative incidence 24% [95% CI 9%-37%]). There was no significant difference in glaucoma-related adverse events between PFV and non-PFV eyes in aphakic participants ≤1 year of age at lensectomy (age-adjusted hazard ratio = 1.20 [95% CI 0.54-2.64], P = .66).
Conclusions: A wide range of visual outcomes for PFV cataract were observed with a 10% probability of achieving age-normal VA. There was an ongoing risk for the development of glaucoma-related adverse events in PFV eyes.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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