Simultaneous T 1 , T 2 and T 2 ⁎ mapping of the liver with multi-shot MI-SAGE.

Autor: Zhang K; Department of Diagnostic & Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic & Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany., Triphan SMF; Department of Diagnostic & Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic & Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany., Wielpütz MO; Department of Diagnostic & Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic & Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany., Ziener CH; Divison of Radiology, German Cancer Research Center, Heidelberg, Germany., Ladd ME; Divison of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany; Faculty of Medicine, Heidelberg University, Heidelberg, Germany., Schlemmer HP; Divison of Radiology, German Cancer Research Center, Heidelberg, Germany., Kauczor HU; Department of Diagnostic & Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic & Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany., Kurz FT; Divison of Radiology, German Cancer Research Center, Heidelberg, Germany., Sedlaczek O; Department of Diagnostic & Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic & Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany; Divison of Radiology, German Cancer Research Center, Heidelberg, Germany. Electronic address: o.sedlaczek@dkfz-heidelberg.de.
Jazyk: angličtina
Zdroj: Magnetic resonance imaging [Magn Reson Imaging] 2024 Jan; Vol. 105, pp. 75-81. Date of Electronic Publication: 2023 Nov 07.
DOI: 10.1016/j.mri.2023.11.004
Abstrakt: Purpose: To apply multi-shot high-resolution multi inversion spin and gradient echo (MI-SAGE) acquisition for simultaneous liver T 1 , T 2 and T 2 * mapping.
Methods: Inversion prepared spin- and gradient-echo EPI was developed with ascending slice order across measurements for efficient acquisition with T 1 , T 2 , and T 2 ⁎ weighting. Multi-shot EPI was also implemented to minimize distortion and blurring while enabling high in-plane resolution. A dictionary-matching approach was used to fit the images to quantitative parameter maps, which were compared to T 1 measured by modified Look-Locker (MOLLI), T 1 measured by variable flip angle (VFA), T 2 measured by multiple echo time-based Half Fourier Single-shot Turbo spin-Echo (HASTE), T 2 measured by radial turbo-spin-echo (rTSE) and T 2 ⁎ measured by multiple gradient echo (MGRE) sequences.
Results: The multi-shot variant of the sequence achieved higher in-plane resolution of 1.7 × 1.7 mm 2 with good image quality in 28 s. Derived quantitative maps showed comparable values to conventional mapping methods. As measured in phantom and in vivo, MOLLI, MESE and MGRE give closest values to MISAGE. VFA, HASTE and rTSE show obvious overestimation.
Conclusions: The proposed multi-shot inversion prepared spin- and gradient-echo EPI sequence allows for high-resolution quantitative T 1 , T 2 and T 2 liver tissue characterization in a single breath-hold scan.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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