[Diagnóstico de alergia inmediata para penicilina: estudio piloto].
| Autor: | Armenta-Morales J; Hospital Universitario de Puebla., Ruiz-Sánchez DM; Hospital Universitario de Puebla., Rivero-Yeverino D; Hospital Universitario de Puebla., Papaqui-Tapia JS; Hospital Universitario de Puebla., Rios-López JJ; Hospital Universitario de Puebla., Lopez-Garcia AI; Hospital Universitario de Puebla., Caballero-López C; Hospital Universitario de Puebla., Pacheco-Jiménez Y; Hospital Universitario de Puebla. |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) [Rev Alerg Mex] 2023 Sep; Vol. 70 (4), pp. 191. |
| DOI: | 10.29262/ram.v70i3.1261 |
| Abstrakt: | Objectives: To confirm the presence of allergy to penicillin and amoxicillin by in vivo exposure tests in patients with a history of immediate reaction to these drugs. Methods: Observational, cross-sectional, descriptive and prolective study. Patients between 12 and 60 years old with a history of immediate reaction after administration of penicillin and/or amoxicillin were included. Skin prick and intradermal tests were performed with benzylpenicilloyl polylysine and penicillin G, as well as oral challenge with amoxicillin. Results: Ten female and 3 male patients were included. The mean age was 39 years. In 84.6% of the cases the last adverse drug reaction occurred 10 years ago and in all cases it manifested with urticaria. Allergy to penicillin was corroborated in only 38.4% of cases. The most frequent adverse reaction after in vivo exposure tests was pruritus in 23%. Conclusions: Patients with suspected penicillin allergy should be evaluated by in vivo exposure testing with major and minor determinants to corroborate or rule out allergic reactions and improve treatment conditions. (Este obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial 4.0 Internacional.) |
| Databáze: | MEDLINE |
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