Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of T H 17 cell immunity.
Autor: | Lin CH; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Wu CJ; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Cho S; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Patkar R; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Huth WJ; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Lin LL; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Chen MC; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA., Israelsson E; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Betts J; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Niedzielska M; Bioscience, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Patel SA; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Duong HG; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Gerner RR; Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Hsu CY; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Catley M; Bioscience, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Maciewicz RA; Bioscience, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Chu H; Department of Pathology, University of California San Diego, La Jolla, CA, USA.; UC San Diego Center for Mucosal Immunology, Allergy, and Vaccines, Chiba University, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA, USA., Raffatellu M; Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; UC San Diego Center for Mucosal Immunology, Allergy, and Vaccines, Chiba University, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA, USA., Chang JT; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.; Department of Medicine, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA., Lu LF; School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA. lifanlu@ucsd.edu.; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA, USA. lifanlu@ucsd.edu.; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA. lifanlu@ucsd.edu. |
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Jazyk: | angličtina |
Zdroj: | Nature immunology [Nat Immunol] 2023 Dec; Vol. 24 (12), pp. 2108-2120. Date of Electronic Publication: 2023 Nov 06. |
DOI: | 10.1038/s41590-023-01667-y |
Abstrakt: | Regulatory T cells (T (© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.) |
Databáze: | MEDLINE |
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