Minimal Change Nephrotic Syndrome Secondary to Methotrexate-associated Hodgkin Lymphoma.

Autor: Iimori M; Department of Nephrology, Japanese Red Cross Kyoto Daiichi Hospital, Japan., Sonomura K; Department of Nephrology, Matsushita Memorial Hospital, Japan., Ueyama Y; Department of Nephrology, Japanese Red Cross Kyoto Daiichi Hospital, Japan., Oobayashi Y; Department of Nephrology, Japanese Red Cross Kyoto Daiichi Hospital, Japan., Adachi H; Department of Nephrology, Matsushita Memorial Hospital, Japan., Nakayama M; Department of Nephrology, Japanese Red Cross Kyoto Daiichi Hospital, Japan.
Jazyk: angličtina
Zdroj: Internal medicine (Tokyo, Japan) [Intern Med] 2024 Jun 15; Vol. 63 (12), pp. 1771-1776. Date of Electronic Publication: 2023 Nov 06.
DOI: 10.2169/internalmedicine.2572-23
Abstrakt: The patient was a 64-year-old man who had been receiving methotrexate (MTX) for rheumatoid arthritis for 8 years. Computed tomography (CT) obtained one month prior to admission revealed numerous enlarged lymph nodes. Lower leg edema appeared two weeks prior to admission. Severe proteinuria was confirmed, and the patient was admitted. A renal biopsy revealed minimal changes in glomeruli. CT on day 14 revealed shrinking lymph nodes, and the patient was diagnosed with Hodgkin lymphoma by a neck lymph node biopsy. This is the first report of secondary minimal change nephrotic syndrome caused by an MTX-associated lymphoproliferative disorder.
Databáze: MEDLINE