BSHI and BTS UK guideline on the detection of alloantibodies in solid organ (and islet) transplantation.

Autor: Battle R; Scottish National Blood Transfusion Service, Edinburgh, UK., Pritchard D; Welsh Blood Service, Pontyclun, UK., Peacock S; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hastie C; Gartnavel General Hospital, Glasgow, UK., Worthington J; Manchester Royal Infirmary, Manchester, UK., Jordan S; National Blood Service Tooting, London, UK., McCaughlan JA; Northern Ireland Blood Transfusion Service, Belfast, UK., Barnardo M; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Cope R; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Collins C; Birmingham Blood Donor Centre, Birmingham, UK., Diaz-Burlinson N; Manchester Royal Infirmary, Manchester, UK., Rosser C; National Blood Service Tooting, London, UK., Foster L; Birmingham Blood Donor Centre, Birmingham, UK., Kallon D; Barts Health Pathology Service, London, UK., Shaw O; Guy's and St Thomas' NHS Foundation Trust, London, UK., Briggs D; Birmingham Blood Donor Centre, Birmingham, UK., Turner D; Scottish National Blood Transfusion Service, Edinburgh, UK., Anand A; Imperial College Healthcare NHS Trust, London, UK., Akbarzad-Yousefi A; National Blood Service Newcastle-upon-Tyne, Newcastle upon Tyne, UK., Sage D; National Blood Service Tooting, London, UK.
Jazyk: angličtina
Zdroj: International journal of immunogenetics [Int J Immunogenet] 2023 Nov; Vol. 50 Suppl 2, pp. 3-63. Date of Electronic Publication: 2023 Nov 02.
DOI: 10.1111/iji.12641
Abstrakt: Solid organ transplantation represents the best (and in many cases only) treatment option for patients with end-stage organ failure. The effectiveness and functioning life of these transplants has improved each decade due to surgical and clinical advances, and accurate histocompatibility assessment. Patient exposure to alloantigen from another individual is a common occurrence and takes place through pregnancies, blood transfusions or previous transplantation. Such exposure to alloantigen's can lead to the formation of circulating alloreactive antibodies which can be deleterious to solid organ transplant outcome. The purpose of these guidelines is to update to the previous BSHI/BTS guidelines 2016 on the relevance, assessment, and management of alloantibodies within solid organ transplantation.
(© 2023 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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